Recombinant Mouse Il2ra Protein (Met1-Lys236), His tagged

• Cat.No.: Il2ra-5424M
• Product Overview: Recombinant mouse CD25 (Met1-Lys236) fused with His tag was expressed in mammalian cells.

Specification

• Description: Enables interleukin-2 binding activity and interleukin-2 receptor activity. Acts upstream of or within several processes, including Notch signaling pathway; activation-induced cell death of T cells; and regulation of T cell proliferation. Located in external side of plasma membrane. Is expressed in bone marrow. Used to study Sjogren's syndrome and inflammatory bowel disease. Human ortholog (s) of this gene implicated in immunodeficiency 41; lymphopenia; multiple sclerosis; type 1 diabetes mellitus; and type 1 diabetes mellitus 10. Orthologous to human IL2RA (interleukin 2 receptor subunit alpha).
• Source: Mammalian cells
• Species: Mouse
• Tag: His
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 28 kDa
• Protein Length: Met1-Lys236
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.6.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: Il2ra interleukin 2 receptor, alpha chain [ Mus musculus (house mouse) ]
• Official Symbol: Il2ra
• Synonyms: IL2RA; interleukin 2 receptor, alpha chain; interleukin-2 receptor subunit alpha; IL2-RA; IL-2-RA; p55 chain; IL-2R alpha chain; IL-2R subunit alpha; IL-2 receptor subunit alpha; CD25; Il2r; Ly-43; MGC130561
• Gene ID: 16184
• mRNA Refseq: NM_008367
• Protein Refseq: NP_032393
• UniProt ID: P01590