Recombinant Human IL2RB Protein

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Recombinant Human IL2RB Protein

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Cat.No. : IL2RB-5196H
Product Overview : Human IL2RB (P14784, Ala 27- Asp 239) partial recombinant protein expressed in HEK293 cells.
Description : The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein. [provided by RefSeq
Source : HEK293
Species : Human
Form : Lyophilized
Molecular Mass : 42 kDa
Endotoxin : < 0.1 ng/μg (1 EU/μg)
Purity : > 90% by SDS-PAGE and HPLC
Applications : SDS-PAGE
Storage : Store at -20 centigrade on dry atmosphere for 2 years. After reconstitution with deionized water, store at 4 centigrade for 1 month or store at -20 centigrade for 12 months. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : Lyophilized PBS, pH 7.2
Gene Name : IL2RB interleukin 2 receptor, beta [ Homo sapiens ]
Official Symbol : IL2RB
Synonyms : IL2RB; interleukin 2 receptor, beta; IL15RB, interleukin 15 receptor, beta; interleukin-2 receptor subunit beta; CD122; p75; IL-2RB; CD122 antigen; IL-2R subunit beta; IL-2 receptor subunit beta; interleukin 15 receptor, beta; high affinity IL-2 receptor beta subunit; high affinity IL-2 receptor subunit beta; IL15RB; P70-75;
Gene ID : 3560
mRNA Refseq : NM_000878
Protein Refseq : NP_000869
MIM : 146710
UniProt ID : P14784

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