Recombinant Human IL7 Protein, His-tagged
Cat.No. : | IL7-121H |
Product Overview : | Recombinant Human Interleukin-7 is produced by our Mammalian expression system and the target gene encoding Asp26-His177 is expressed with a 6His tag at the C-terminus. |
- Specification
- Gene Information
- Related Products
Description : | Human Interleukin 7 (IL-7) is a potent lymphoid cell growth factor stimulating the proliferation of lymphoid progenitors. IL7 can associate with the hepatocyte growth factor (HGF) to form a hybrid cytokine that functions as a pre-pro-B cell growth-stimulating factor. Human IL7 cDNA encodes a 177 amino acid precursor protein containing a 25 amino acid signal peptide and a 152 amino acid mature protein. Human and mouse IL7 share 65% sequence identity in the mature region and both exhibit cross-species activity. IL-7 signals via IL-7 receptor (IL7R) activating multiple pathways including JaK/STAT and PI3K/AKT, which regulate lymphocyte survival, glucose uptake, proliferation, and differentiation. IL-7 is also associated with cytoplasmic IL2-R gamma for signal transduction. |
Source : | Human Cells |
Species : | Human |
Tag : | His |
Form : | Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
Protein Length : | Asp26-His177 |
AA Sequence : | DCDIEGKDGKQYESVLMVSIDQLLD SMKEIGSNCLNNEFNFFKRHICDAN KEGMFLFRAARKLRQFL KMNSTGDFDLHLLKVSEGTTILLNC TGQVKGRKPAALGEAQPTKSLEENK SLKEQKKLNDLCFLKRL LQEIKTCWNKILMGTKEHVDHHHHH H |
Endotoxin : | Less than 0.1 ng/ug (1 EU/ug). |
Purity : | >95% |
Storage : | Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days. Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months. Always centrifuge tubes before opening. Do not mix by vortex or pipetting |
Reconstitution : | It is not recommended to reconstitute to a concentration less than 100μg/ml. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Quality Statement : | Greater than 95% as determined by reducing SDS-PAGE. |
Shipping : | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Gene Name : | IL7 interleukin 7 [ Homo sapiens (human) ] |
Official Symbol : | IL7 |
Synonyms : | Interleukin-7; IL-7 |
Gene ID : | 3574 |
mRNA Refseq : | NM_000880.4 |
Protein Refseq : | NP_000871.1 |
MIM : | 146660 |
UniProt ID : | P13232 |
Products Types
◆ Recombinant Protein | ||
Il7-1683M | Recombinant Mouse Il7 Protein, His-tagged | +Inquiry |
IL7-518H | Recombinant Human IL7 Protein | +Inquiry |
Il7-62M | Active Recombinant Mouse Il7 Protein (Glu26-Ile154), C-His tagged, Animal-free, Carrier-free | +Inquiry |
IL7-069H | Active Recombinant Human IL7 Protein | +Inquiry |
IL7-2172M | Recombinant Mouse IL7 Protein | +Inquiry |
◆ Lysates | ||
IL7-5223HCL | Recombinant Human IL7 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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