Recombinant Human Interleukin 17A, His-tagged
Cat.No. : | IL17A-426H |
Product Overview : | Interleukin-17A Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 132 amino acids fragment (24-155) having a molecular weight of 21.5kDa and fused with a 4.5kDa amino-terminal hexahistidine tag. The IL-17A His is purified by proprietary chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | IL17A-426H |
Description : | IL17 is a proinflammatory cytokine produced by activated T cells. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases. Interleukin-17 can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. |
Source : | Human |
Host : | Escherichia Coli. |
Form : | Interleukin -17 His-Tag protein is supplied in 1xPBS, 50% glycerol. |
Purity : | Greater than 95.0% as determined by SDS-PAGE. |
Physical Appearance : | Sterile Filtered clear solution. |
Storage : | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles. |
Pathways : | Cytokine-cytokine receptor interaction |
Gene Name : | IL17A interleukin 17A [ Homo sapiens ] |
Official Symbol : | IL17A |
Synonyms : | IL17; CTLA-8; IL-17; IL-17A; Cytotoxic T-lymphocyte-associated antigen 8; Interleukin-17A, CTLA8; Interleukin-17A Precursor; IL17A; interleukin 17A |
Gene ID : | 3605 |
mRNA Refseq : | NM_002190 |
Protein Refseq : | NP_002181 |
MIM : | 603149 |
UniProt ID : | Q16552 |
Chromosome Location : | 6p12 |
Function : | Induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of the intracellular adhesion molecule-1 (ICAM-1) in fibroblasts. |
Products Types
◆ Recombinant Protein | ||
IL17A-100I | Active Recombinant Human IL17A Protein (136 aa) | +Inquiry |
Il17a-52M | Active Recombinant Mouse Il17a Protein (Ala26-Ala158), C-His tagged, Animal-free, Carrier-free | +Inquiry |
IL17A-48H | Recombinant Human IL17A Protein | +Inquiry |
IL17A-001C | Recombinant Cynomolgus Monkey IL17A Protein | +Inquiry |
IL17A-137H | Active Recombinant Human IL17A Protein | +Inquiry |
◆ Lysates | ||
IL17A-001HCL | Recombinant Human IL17A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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