Recombinant Human Interleukin 17B IL17B-166H

Recombinant Human Interleukin 17B

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Cat.No. : IL17B-166H Optional Service: Optional requirements on this protein
Product Overview : Recombinant human IL-17B produced inE.coliis a 36.6 kDa disulfide-linked homodimer of two 161 amino acid polypeptide chains.
Description : IL-17B is a disulfide-linked homodimer of two 161 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17B is expressed by T-cells and has been shown to stimulate release of TNF-alpha and IL-1beta from cells of the monocyte lineage.
Source : E.coli.
Purity : > 98% by SDS-PAGE and HPLC analysis.
Endotoxin Level : < 0.1 ng per ug of IL-17B.
Stabilizer : None.
Formulation : Lyophilized.
Biological Activity : Determined by its ability to induce IL-8 in human PBMCs using a concentration range of 10ng-100ng.
Reconstitution : The human IL-17B should be reconstituted in water to a concentration of 0.1-1.0 mg/ml. This solution can be diluted in water or other buffer solutions or stored at -20℃.
Stability : The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20℃. Reconstituted human IL-17B should be stored in working aliquots at -20℃. Avoid repeated freeze-thaw cycles.
Gene Name : IL17B interleukin 17B [ Homo sapiens ]
Synonyms : IL17B; interleukin 17B; ZCYTO7; IL-20; Interleukin-17B;IL-17B; Cytokine-like protein Zcyto7; Neuronal interleukin-17-related factor; Interleukin-20; MGC138900; MGC138901; Neuronal interleukin-17-related factor; interleukin-17 beta
Gene ID : 27190
mRNA Refseq : NM_014443
Protein Refseq : NP_055258
MIM : 604627
UniProt ID : Q9UHF5
Chromosome Location : 5q33.1
Pathway : Cytokine-cytokine receptor interaction
Function : cytokine activity;signal transducer activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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