Recombinant Human Interleukin 17B
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Cat.No. : | IL17B-166H Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant human IL-17B produced inE.coliis a 36.6 kDa disulfide-linked homodimer of two 161 amino acid polypeptide chains. |
Description : | IL-17B is a disulfide-linked homodimer of two 161 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17B is expressed by T-cells and has been shown to stimulate release of TNF-alpha and IL-1beta from cells of the monocyte lineage. |
Source : | E.coli. |
Purity : | > 98% by SDS-PAGE and HPLC analysis. |
Endotoxin Level : | < 0.1 ng per ug of IL-17B. |
Stabilizer : | None. |
Formulation : | Lyophilized. |
Biological Activity : | Determined by its ability to induce IL-8 in human PBMCs using a concentration range of 10ng-100ng. |
Reconstitution : | The human IL-17B should be reconstituted in water to a concentration of 0.1-1.0 mg/ml. This solution can be diluted in water or other buffer solutions or stored at -20℃. |
Stability : | The lyophilized protein is stable for a few weeks at room temperature, but best stored at -20℃. Reconstituted human IL-17B should be stored in working aliquots at -20℃. Avoid repeated freeze-thaw cycles. |
Gene Name : | IL17B interleukin 17B [ Homo sapiens ] |
Synonyms : | IL17B; interleukin 17B; ZCYTO7; IL-20; Interleukin-17B;IL-17B; Cytokine-like protein Zcyto7; Neuronal interleukin-17-related factor; Interleukin-20; MGC138900; MGC138901; Neuronal interleukin-17-related factor; interleukin-17 beta |
Gene ID : | 27190 |
mRNA Refseq : | NM_014443 |
Protein Refseq : | NP_055258 |
MIM : | 604627 |
UniProt ID : | Q9UHF5 |
Chromosome Location : | 5q33.1 |
Pathway : | Cytokine-cytokine receptor interaction |
Function : | cytokine activity;signal transducer activity |
◆ Recombinant Protein
IL17B-150H | Recombinant Active Human IL17B Protein, His-tagged(C-ter) | +Inquiry |
IL17B-317H | Active Recombinant Human interleukin 17B, HIgG1 Fc-tagged | +Inquiry |
Il17b-513M | Recombinant Mouse Il17b, Fc-tagged | +Inquiry |
IL17B-315H | Active Recombinant Human interleukin 17B, MIgG2a Fc-tagged | +Inquiry |
IL17B-562H | Recombinant Human interleukin 17B, His-tagged | +Inquiry |
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◆ Lysates
IL17B-5244HCL | Recombinant Human IL17B 293 Cell Lysate | +Inquiry |
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IL10IL10RAIL10RBIL11IL11RAIl11ra1IL12IL12AIL12BIL12RB1IL13IL13RA1IL13RA2IL15IL15RAIL16IL17AIL17BIl17cIL17DIl17fIL17RAIL17RDIL18IL18BPIL18R1IL18RAPIl19Il1aIl1bIL1F10IL1R1Il1r2IL1RAPIL1RAPL1IL1RAPL2IL1RL1IL1RL2Il1rnIL2Il20IL20RAIL21IL21RIL22IL22BPIL22RA1IL22RA2IL23AIL24Il25IL27IL27RAIL28AIl28bIL29IL2RAIL2RBIl2rgIL3IL31IL32Il33Il34IL3RAIL4IL4RIl4raIl5IL5RAIl6IL6RIl6raIL6STIl7IL7RIL8IL9IL36AIl12rb2IL17RBIL23RIL26IL31RAIL36BIL36GIL36RNIL37IL9RIL17RCIL17REIL28RAIL4I1IL20RBIL17RELIl11ra2IL27bIL7RAIl23a&Il12b
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