Recombinant Human Interleukin 2 Receptor, Alpha
Cat.No. : | IL2RA-1237H |
Product Overview : | Recombinant human IL2RA is a 24.8 kDa protein containing 219 aminoacid residues consisting of only the extracellular domain of IL2RA. Due to glycosylation, IL2RA has an approximate molecular weight of 31 kDabased on SDS-PAGE gel and Mass Spectrometry. |
- Specification
- Gene Information
- Related Products
Cat. No. : | IL2RA-1237H |
Description : | TheIL-2 receptor system consists of three non-covalently linked subunits termed IL2RA, IL-2R beta, and IL-2R gamma. The IL2RA is a type I transmembrane protein consistingof a 219 amino acid extracellular domain, a 19 amino acid transmembranedomain and a 13 amino acid intracellular domain, which is not involved in thetransduction of IL-2 signals. |
Source : | Insect cells |
Species : | Human |
Purity : | > 95.0% asdetermined by RP-HPLC and SDS-PAGE analyses |
Endotoxin Level : | <0.1 ng per µg ofIL2RA |
Biological Activity : | Determined by itsability to increase the proliferation effect of IL-2 in mouse CTLL-2 cells.In the presence of 1 ng/ml of recombinant IL-2, the expected ED50for this effect is between 0.5-1.5 µg/ml. |
OfficialSymbol : | IL2RA |
Gene Name : | IL2RA interleukin 2 receptor,alpha [ Homo sapiens ] |
Synonyms : | IL2RA;interleukin 2 receptor, alpha; CD25; IL2R; TCGFR; IDDM10; Interleukin-2receptor alpha chain; IL-2 receptor alpha subunit; IL-2-RA; IL2-RA; p55; TACantigen; OTTHUMP00000019030; OTTHUMP00000044870; CD25 antigen; IL-2 receptoralpha subunit; Interleukin-2 receptor |
Gene ID : | 3559 |
mRNA Refseq : | NM_000417 |
Protein Refseq : | NP_000408 |
MIM : | 147730 |
UniProt ID : | P01589 |
Chromosome Location : | 10p15-p14 |
Pathway : | Arf6 trafficking events; Cytokine Signalingin Immune system; Endocytosis; HTLV-I infection; Hematopoietic cell lineage; IL-2Signaling Pathway; IL12 signaling mediated by STAT4; IL2 signaling eventsmediated by PI3K; IL2-mediated signaling events; Immune System; InflammatoryResponse Pathway; Interleukin receptor SHC signaling; Interleukin-2 signaling;Jak-STAT signaling pathway; Measles |
Function : | drug binding; interleukin-2 binding; interleukin-2receptor activity; receptor activity |
Products Types
◆ Recombinant Protein | ||
Il2ra-4513M | Recombinant Mouse Il2ra Protein, His (Fc)-Avi-tagged | +Inquiry |
IL2RA-2698R | Recombinant Rat IL2RA Protein, His (Fc)-Avi-tagged | +Inquiry |
IL2RA-942R | Recombinant Rat IL2RA Protein (Met1-Gln235), His-tagged | +Inquiry |
IL2RA-43H | Recombinant Human IL2RA Protein, C-Avi&His tagged, Biotinylated | +Inquiry |
IL2RA-5198H | Recombinant Human IL2RA Protein | +Inquiry |
◆ Lysates | ||
IL2RA-1015CCL | Recombinant Cynomolgus IL2RA cell lysate | +Inquiry |
IL2RA-2907HCL | Recombinant Human IL2RA cell lysate | +Inquiry |
IL2RA-2024MCL | Recombinant Mouse IL2RA cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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