Recombinant Human Interleukin 2 Receptor, Beta IL2RB-1643H

Recombinant Human Interleukin 2 Receptor, Beta

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Cat.No. : IL2RB-1643H Optional Service: Optional requirements on this protein
Description : Interleukin 2 receptor beta, also known as IL2RB, is a novel glycoprotein that has the ability to bind IL-2 alone and to associate with Tac antigen (IL-2R alpha) to form high-affinity IL-2 receptors. IL-2R beta is expressed on both circulating T lymphocytes and large granular lymphocytes. IL-2R beta mediates the initial phase of induction of lymphokine activated killer (LAK), natural killer (NK), and proliferative activities.
Source : Sf 21 Insect Cells.
State Of Matter : Lyophilized.
Purity : >97% by SDS Page and analyzed by silver stain.
Endotoxin : <1.0 EU/µg as determined by the LAL method.
Molecular Weight : The predicted molecular weight of Recombinant Human IL-2 sRβ is Mr 25 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 29-31 kDa.
Storage And Stability : This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
PDB rendering based on 2b5i. :

Gene Name : IL2RB interleukin 2 receptor, beta [ Homo sapiens ]
Synonyms : IL2RB; interleukin 2 receptor, beta; CD122; P70-75; interleukin 2 receptor beta; CD122 antigen; high affinity IL-2 receptor beta subunit; OTTHUMP00000028799; IL-2 receptor
Gene ID : 3560
mRNA Refseq : NM_000878
Protein Refseq : NP_000869
MIM : 146710
UniProt ID : P14784
Chromosome Location : 22q13
Pathway : Cytokine-cytokine receptor interaction; Endocytosis; Jak-STAT signaling pathway
Function : interleukin-2 receptor activity; receptor activity
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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