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Recombinant Human Interleukin 2 Receptor, Beta
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Cat.No. : | IL2RB-1643H Optional Service: Optional requirements on this protein |
Description : | Interleukin 2 receptor beta, also known as IL2RB, is a novel glycoprotein that has the ability to bind IL-2 alone and to associate with Tac antigen (IL-2R alpha) to form high-affinity IL-2 receptors. IL-2R beta is expressed on both circulating T lymphocytes and large granular lymphocytes. IL-2R beta mediates the initial phase of induction of lymphokine activated killer (LAK), natural killer (NK), and proliferative activities. |
Source : | Sf 21 Insect Cells. |
State Of Matter : | Lyophilized. |
Purity : | >97% by SDS Page and analyzed by silver stain. |
Endotoxin : | <1.0 EU/µg as determined by the LAL method. |
Molecular Weight : | The predicted molecular weight of Recombinant Human IL-2 sRβ is Mr 25 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 29-31 kDa. |
Storage And Stability : | This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70°C. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
PDB rendering based on 2b5i. : |
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Gene Name : | IL2RB interleukin 2 receptor, beta [ Homo sapiens ] |
Synonyms : | IL2RB; interleukin 2 receptor, beta; CD122; P70-75; interleukin 2 receptor beta; CD122 antigen; high affinity IL-2 receptor beta subunit; OTTHUMP00000028799; IL-2 receptor |
Gene ID : | 3560 |
mRNA Refseq : | NM_000878 |
Protein Refseq : | NP_000869 |
MIM : | 146710 |
UniProt ID : | P14784 |
Chromosome Location : | 22q13 |
Pathway : | Cytokine-cytokine receptor interaction; Endocytosis; Jak-STAT signaling pathway |
Function : | interleukin-2 receptor activity; receptor activity |
◆ Recombinant Protein
IL2RB-420H | Recombinant Human IL2RB Protein (Met1-Asp239), His-tagged | +Inquiry |
IL2RB-29H | Recombinant Human IL2RB Protein, C-6His-Avi tagged, Biotinylated | +Inquiry |
IL2RB-619C | Recombinant Cynomolgus IL2RB Protein, His-tagged | +Inquiry |
IL2RB-1257M | Recombinant Mouse IL2RB Protein, His-tagged | +Inquiry |
IL2RB-454R | Recombinant Rhesus IL2RB Protein, Fc-tagged | +Inquiry |
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◆ Lysates
IL2RB-744MCL | Recombinant Mouse IL2RB cell lysate | +Inquiry |
IL2RB-2906HCL | Recombinant Human IL2RB cell lysate | +Inquiry |
IL2RB-741CCL | Recombinant Canine IL2RB cell lysate | +Inquiry |
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IL10IL10RAIL10RBIL11IL11RAIl11ra1IL12IL12AIL12BIL12RB1IL13IL13RA1IL13RA2IL15IL15RAIL16IL17AIL17BIl17cIL17DIl17fIL17RAIL17RDIL18IL18BPIL18R1IL18RAPIl19Il1aIl1bIL1F10IL1R1Il1r2IL1RAPIL1RAPL1IL1RAPL2IL1RL1IL1RL2Il1rnIL2Il20IL20RAIL21IL21RIL22IL22BPIL22RA1IL22RA2IL23AIL24Il25IL27IL27RAIL28AIl28bIL29IL2RAIL2RBIl2rgIL3IL31IL32Il33Il34IL3RAIL4IL4RIl4raIl5IL5RAIl6IL6RIl6raIL6STIl7IL7RIL8IL9IL36AIl12rb2IL17RBIL23RIL26IL31RAIL36BIL36GIL36RNIL37IL9RIL17RCIL17REIL28RAIL4I1IL20RBIL17RELIl11ra2IL27bIL7RAIl23a&Il12b
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