Recombinant Human KRT16 Protein, GST-tagged

• Cat.No.: KRT16-4869H
• Product Overview: Human KRT16 full-length ORF ( NP_005548.2, 1 a.a. - 473 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 77.7 kDa
• AA Sequence: MTTCSRQFTSSSSMKGSCGIGGGIG GGSSRISSVLAGGSCRAPSTYGGGL SVSSRFSSGGACGLGGGYGGGFSSS SSFGSGFGGGYGGGLGAGFGGGLGA GFGGGFAGGDGLLVGSEKVTMQNLN DRLASYLDKVRALEEANADLEVKIR DWYQRQRPSEIKDYSPYFKTIEDLR NKIIAATIENAQPILQIDNARLAAD DFRTKYEHELALRQTVEADVNGLRR VLDELTLARTDLEMQIEGLKEELAY LRKNHEEEMLALRGQTGGDVNVEMD AAPGVDLSRILNEMRDQYEQMAEKN RRDAETWFLSKTEELNKEVASNSEL VQSSRSEVTELRRVLQGLEIELQSQ LSMKASLENSLEETKGRYCMQLSQI QGLIGSVEEQLAQLRCEMEQQSQEY QILLDVKTRLEQEIATYRRLLEGED AHLSSQQASGQSYSSREVFTSSSSS SSRQTRPILKEQSSSSFSQGQSS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: KRT16 keratin 16 [ Homo sapiens ]
• Official Symbol: KRT16
• Synonyms: KRT16; keratin 16; keratin, type I cytoskeletal 16; CK-16; keratin-16; cytokeratin 16; cytokeratin-16; focal non-epidermolytic palmoplantar keratoderma; K16; CK16; K1CP; NEPPK; FNEPPK; KRT16A
• Gene ID: 3868
• mRNA Refseq: NM_005557
• Protein Refseq: NP_005548