Recombinant Human LDHB Protein, His-tagged

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Recombinant Human LDHB Protein, His-tagged

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Cat.No. : LDHB-931H
Product Overview : Recombinant Human LDHB(Ala2-Leu334), transcript variant 2, fused with His tag at C-terminal was expressed in E. coli.
Description : This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.
Source : E. coli
Tag : His
Form : 20mM Tris-HCl, 100mM NaCl, pH 8.0. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Molecular Mass : 38.8 kDa
Endotoxin : < 0.1 EU per µg protein as determined by LAL test
Purity : >95% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : LDHB lactate dehydrogenase B [ Homo sapiens ]
Official Symbol : LDHB
Synonyms : LDHB; lactate dehydrogenase B; L-lactate dehydrogenase B chain; LDH heart subunit; lactate dehydrogenase H chain; renal carcinoma antigen NY-REN-46; LDH-B; LDH-H; LDHBD; TRG-5;
Gene ID : 3945
mRNA Refseq : NM_001174097
Protein Refseq : NP_001167568
MIM : 150100
UniProt ID : P07195
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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