Recombinant Human MAP2K4 Protein, MYC/DDK-tagged MAP2K4-394H

Recombinant Human MAP2K4 Protein, MYC/DDK-tagged

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Cat.No. : MAP2K4-394H Optional Service: Optional requirements on this protein
Product Overview : Recombinant human MAP2K4 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
Description : This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass : 44.1 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : mitogen-activated protein kinase kinase 4 [ Homo sapiens ]
Official Symbol : MAP2K4
Synonyms : JNKK; JNKK1; MAPKK4; MEK4; MKK4; PRKMK4; SAPKK-1; SAPKK1; SEK1; SERK1; SKK1
Gene ID : 6416
mRNA Refseq : NM_003010.2
Protein Refseq : NP_003001.1
MIM : 601335
UniProt ID : P45985
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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