Recombinant Human MAP3K2
Cat.No. : | MAP3K2-30191TH |
Product Overview : | Recombinant full length Human MEKK2 with an N-terminal proprietary tag, expressed by baculovirus in Sf9 insect cells. MW ~115kDa. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process. |
Biological activity : | Specific activity: 226nmol/min/mg. |
Form : | Liquid |
Storage buffer : | Preservative: NoneConstituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM PMSF, pH 7.5 |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequence Similarities : | Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.Contains 1 OPR domain.Contains 1 protein kinase domain. |
Gene Name : | MAP3K2 mitogen-activated protein kinase kinase kinase 2 [ Homo sapiens ] |
Official Symbol : | MAP3K2 |
Synonyms : | MAP3K2; mitogen-activated protein kinase kinase kinase 2; MEKK2; MAP/ERK kinase kinase 2; MEKK2B; |
Gene ID : | 10746 |
mRNA Refseq : | NM_006609 |
Protein Refseq : | NP_006600 |
MIM : | 609487 |
Uniprot ID : | Q9Y2U5 |
Chromosome Location : | 2q21.1 |
Pathway : | EGFR1 Signaling Pathway, organism-specific biosystem; ErbB1 downstream signaling, organism-specific biosystem; Gap junction, organism-specific biosystem; Gap junction, conserved biosystem; GnRH signaling pathway, organism-specific biosystem; |
Function : | ATP binding; MAP kinase kinase kinase activity; metal ion binding; nucleotide binding; protein kinase activity; |
Products Types
◆ Recombinant Protein | ||
Map3k2-3929M | Recombinant Mouse Map3k2 Protein, Myc/DDK-tagged | +Inquiry |
MAP3K2-1358H | Recombinant Human MAP3K2 Protein, His (Fc)-Avi-tagged | +Inquiry |
MAP3K2-351H | Recombinant Human MAP3K2, GST-tagged, Active | +Inquiry |
MAP3K2-1258H | Recombinant Human Mitogen-Activated Protein Kinase Kinase Kinase 2, GST-tagged | +Inquiry |
◆ Lysates | ||
MAP3K2-4506HCL | Recombinant Human MAP3K2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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