Recombinant Human MGAT5 Protein (AA 31-741), N-6×His/GFP tagged
Cat.No. : | MGAT5-04H |
Product Overview : | Recombinant Human MGAT5 Protein (AA 31-741) with N-6×His/GFP tag was expressed in HEK293. |
- Specification
- Gene Information
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Description : | The protein encoded by this gene belongs to the glycosyltransferase family. It catalyzes the addition of beta-1,6-N-acetylglucosamine to the alpha-linked mannose of biantennary N-linked oligosaccharides present on the newly synthesized glycoproteins. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. Alterations of the oligosaccharides on cell surface glycoproteins cause significant changes in the adhesive or migratory behavior of a cell. Increase in the activity of this enzyme has been correlated with the progression of invasive malignancies. |
Source : | HEK293 |
Species : | Human |
Tag : | N-6×His, GFP |
Molecular Mass : | ~115 kDa |
Protein Length : | AA 31-741 |
AA Sequence : | HFTIQQRTQPESSSMLREQILDLSK RYIKALAEENRNVVDGPYAGVMTAY DLKKTLAVLLDNILQRIGKLESKVD NLVVNGTGTNSTNSTTAVPSLVALE KINVADIINGAQEKCVLPPMDGYPH CEGKIKWMKDMWRSDPCYADYGVDG STCSFFIYLSEVENWCPHLPWRAKN PYEEADHNSLAEIRTDFNILYSMMK KHEEFRWMRLRIRRMADAWIQAIKS LAEKQNLEKRKRKKVLVHLGLLTKE SGFKIAETAFSGGPLGELVQWSDLI TSLYLLGHDIRISASLAELKEIMKK VVGNRSGCPTVGDRIVELIYIDIVG LAQFKKTLGPSWVHYQCMLRVLDSF GTEPEFNHANYAQSKGHKTPWGKWN LNPQQFYTMFPHTPDNSFLGFVVEQ HLNSSDIHHINEIKRQNQSLVYGKV DSFWKNKKIYLDIIHTYMEVHATVY GSSTKNIPSYVKNHGILSGRDLQFL LRETKLFVGLGFPYEGPAPLEAIAN GCAFLNPKFNPPKSSKNTDFFIGKP TLRELTSQHPYAEVFIGRPHVWTVD LNNQEEVEDAVKAILNQKIEPYMPY EFTCEGMLQRINAFIEKQDFCHGQV MWPPLSALQVKLAEPGQSCKQVCQE SQLICEPSFFQHLNKDKDMLKYKVT CQSSELAKDILVPSFDPKNKHCVFQ GDLLLFSCAGAHPRHQRVCPCRDFI KGQVALCKDCL |
Purity : | >95%, by SDS-PAGE as visualized by Coomassie Blue Staining |
Stability : | 6 months if stored at -80 centigrade. Avoid repeated freeze thaws. |
Concentration : | 1 mg/mL |
Storage Buffer : | Supplied as a 0.2 μm filtered solution in 20mM HEPES pH 7.0 and 100mM NaCl buffer, with 10% Glycerol. |
Preservative : | 0.05 % NaN3 |
Shipping : | This product is shipped as 0.2μm filtered product on dry ice. |
Gene Name : | MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase [ Homo sapiens (human) ] |
Official Symbol : | MGAT5 |
Synonyms : | MGAT5; mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase; alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A; GNT V; glcNAc-T V; N-acetylglucosaminyl-transferase V; mannoside acetylglucosaminyltransferase 5; alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase; GNT-V; GNT-VA; FLJ31899; FLJ43217; DKFZp686B24166; |
Gene ID : | 4249 |
mRNA Refseq : | NM_002410 |
Protein Refseq : | NP_002401 |
MIM : | 601774 |
UniProt ID : | Q09328 |
Products Types
◆ Recombinant Protein | ||
MGAT5-4363H | Recombinant Human MGAT5 Protein, GST-tagged | +Inquiry |
MGAT5-1120H | Active Recombinant Human MGAT5 protein, His-tagged | +Inquiry |
MGAT5-4300Z | Recombinant Zebrafish MGAT5 | +Inquiry |
◆ Lysates | ||
MGAT5-2067HCL | Recombinant Human MGAT5 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionMGAT5 modulates immune responses.
MGAT5 is key for glycoprotein glycosylation.
It affects cell signaling by altering glycosylation patterns.
Altered MGAT5 activity is linked to cancer progression.
Genetic changes in MGAT5 impact glycosylation and cell processes.
Targeting MGAT5 could treat diseases involving abnormal glycosylation.
MGAT5 collaborates with other enzymes in glycosylation.
Customer Reviews (3)
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