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Recombinant Human MGAT5 Protein (AA 31-741), N-6×His/GFP tagged

Cat.No. : MGAT5-04H
Product Overview : Recombinant Human MGAT5 Protein (AA 31-741) with N-6×His/GFP tag was expressed in HEK293.
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Description : The protein encoded by this gene belongs to the glycosyltransferase family. It catalyzes the addition of beta-1,6-N-acetylglucosamine to the alpha-linked mannose of biantennary N-linked oligosaccharides present on the newly synthesized glycoproteins. It is one of the most important enzymes involved in the regulation of the biosynthesis of glycoprotein oligosaccharides. Alterations of the oligosaccharides on cell surface glycoproteins cause significant changes in the adhesive or migratory behavior of a cell. Increase in the activity of this enzyme has been correlated with the progression of invasive malignancies.
Source : HEK293
Species : Human
Tag : N-6×His, GFP
Molecular Mass : ~115 kDa
Protein Length : AA 31-741
AA Sequence : HFTIQQRTQPESSSMLREQILDLSK RYIKALAEENRNVVDGPYAGVMTAY DLKKTLAVLLDNILQRIGKLESKVD NLVVNGTGTNSTNSTTAVPSLVALE KINVADIINGAQEKCVLPPMDGYPH CEGKIKWMKDMWRSDPCYADYGVDG STCSFFIYLSEVENWCPHLPWRAKN PYEEADHNSLAEIRTDFNILYSMMK KHEEFRWMRLRIRRMADAWIQAIKS LAEKQNLEKRKRKKVLVHLGLLTKE SGFKIAETAFSGGPLGELVQWSDLI TSLYLLGHDIRISASLAELKEIMKK VVGNRSGCPTVGDRIVELIYIDIVG LAQFKKTLGPSWVHYQCMLRVLDSF GTEPEFNHANYAQSKGHKTPWGKWN LNPQQFYTMFPHTPDNSFLGFVVEQ HLNSSDIHHINEIKRQNQSLVYGKV DSFWKNKKIYLDIIHTYMEVHATVY GSSTKNIPSYVKNHGILSGRDLQFL LRETKLFVGLGFPYEGPAPLEAIAN GCAFLNPKFNPPKSSKNTDFFIGKP TLRELTSQHPYAEVFIGRPHVWTVD LNNQEEVEDAVKAILNQKIEPYMPY EFTCEGMLQRINAFIEKQDFCHGQV MWPPLSALQVKLAEPGQSCKQVCQE SQLICEPSFFQHLNKDKDMLKYKVT CQSSELAKDILVPSFDPKNKHCVFQ GDLLLFSCAGAHPRHQRVCPCRDFI KGQVALCKDCL
Purity : >95%, by SDS-PAGE as visualized by Coomassie Blue Staining
Stability : 6 months if stored at -80 centigrade. Avoid repeated freeze thaws.
Concentration : 1 mg/mL
Storage Buffer : Supplied as a 0.2 μm filtered solution in 20mM HEPES pH 7.0 and 100mM NaCl buffer, with 10% Glycerol.
Preservative : 0.05 % NaN3
Shipping : This product is shipped as 0.2μm filtered product on dry ice.
Gene Name : MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase [ Homo sapiens (human) ]
Official Symbol : MGAT5
Synonyms : MGAT5; mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase; alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A; GNT V; glcNAc-T V; N-acetylglucosaminyl-transferase V; mannoside acetylglucosaminyltransferase 5; alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase; GNT-V; GNT-VA; FLJ31899; FLJ43217; DKFZp686B24166;
Gene ID : 4249
mRNA Refseq : NM_002410
Protein Refseq : NP_002401
MIM : 601774
UniProt ID : Q09328

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What role does MGAT5 play in immune responses? 07/24/2022

MGAT5 modulates immune responses.

What is the primary role of MGAT5 in glycoprotein synthesis? 12/24/2021

MGAT5 is key for glycoprotein glycosylation.

How does MGAT5 contribute to cell signaling and communication? 09/09/2021

It affects cell signaling by altering glycosylation patterns.

What is the impact of altered MGAT5 activity on cancer progression? 09/06/2021

Altered MGAT5 activity is linked to cancer progression.

How do genetic variations in MGAT5 affect cellular functions? 03/22/2020

Genetic changes in MGAT5 impact glycosylation and cell processes.

What potential therapeutic applications arise from targeting MGAT5 in diseases? 01/29/2020

Targeting MGAT5 could treat diseases involving abnormal glycosylation.

How does MGAT5 interact with other enzymes in glycosylation pathways? 06/08/2019

MGAT5 collaborates with other enzymes in glycosylation.

Customer Reviews (3)

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02/19/2023

    Trusted for research integrity, a dependable research collaborator.

    10/07/2020

      Efficient service, accelerates research progress.

      11/24/2018

        Outstanding accuracy, an essential part of our research.

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