| Description : |
This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
His |
| Form : |
Lyophilized |
| Molecular Mass : |
33 kDa |
| Protein Length : |
630 |
| AA Sequence : |
MALPTARPLLGSCGTPALGSLLFLL FSLGWVQPSRTLAGETGQEAAPLDG VLANPPNISSLSPRQLLGFPCAEVS GLSTERVRELAVALAQKNVKLSTEQ LRCLAHRLSEPPEDLDALPLDLLLF LNPDAFSGPQACTRFFSRITKANVD LLPRGAPERQRLLPAALACWGVRGS LLSEADVRALGGLACDLPGRFVAES AEVLLPRLVSCPGPLDQDQQEAARA ALQGGGPPYGPPSTWSVSTMDALRG LLPVLGQPIIRSIPQGIVAAWRQRS SRDPSWRQPERTILRPRFRREVEKT ACPSGKKAREIDESLIFYKKWELEA CVDAALLATQMDRVNAIPFTYEQLD VLKHKLDELYPQGYPESVIQHLGYL FLKMSPEDIRKWNVTSLETLKALLE VNKGHEMSPQAPRRPLPQVATLIDR FVKGRGQLDKDTLDTLTAFYPGYLC SLSPEELSSVPPSSIWAVRPQDLDT CDPRQLDVLYPKARLAFQNMNGSEY FVKIQSFLGGAPTEDLKALSQQNVS MDLATFMKLRTDAVLPLTVAEVQKL LGPHVEGLKAEERHRPVRDWILRQR QDDLDTLGLGLQGGIPNGYLVLDLS MQEALSGTPCLLGPGPVLTVLALLL ASTLA |
| Purity : |
> 98% |
| Applications : |
WB; ELISA; FACS; FC |
| Stability : |
This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use. |
| Storage : |
At -20 centigrade. |
| Concentration : |
1 mg/mL |
| Storage Buffer : |
PBS (pH 7.4-7.5). Sterile-filtered colorless solution. |
| Reconstitution : |
Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance. |
