Active Recombinant Human NEK1 Protein, GST-tagged

• Cat.No.: NEK1-9928H
• Product Overview: Recombinant human NEK1 (1-477) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Description: The protein encoded by this gene is a serine/threonine kinase involved in cell cycle regulation. The encoded protein is found in a centrosomal complex with FEZ1, a neuronal protein that plays a role in axonal development. Defects in this gene are a cause of polycystic kidney disease (PKD). Several transcript variants encoding different isoforms have been found for this gene.
• Source: Insect cell
• Species: Human
• Tag: GST
• Bio-activity: 11 nmol/min/mg
• Molecular Mass: 85 kDa
• Protein length: 1-477
• Purity: > 85%
• Stability: One year at -70 centigrade from fate of shipment.
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.05 μg/μL
• Storage Buffer: 50mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.

Gene Information

• Gene Name: NEK1 NIMA related kinase 1 [ Homo sapiens (human) ]
• Official Symbol: NEK1
• Synonyms: NEK1; NIMA related kinase 1; ALS24; SRPS2; SRTD6; SRPS2A; NY-REN-55; serine/threonine-protein kinase Nek1; NIMA (never in mitosis gene a)-related kinase 1; never in mitosis A-related kinase 1; nimA-related protein kinase 1; protein-serine/threonine kinase; renal carcinoma antigen NY-REN-55; EC 2.7.11.1
• Gene ID: 4750
• mRNA Refseq: NM_012224
• Protein Refseq: NP_036356
• MIM: 604588
• UniProt ID: Q96PY6