Recombinant Human PDE1B Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | PDE1B-2292H |
Product Overview : | PDE1B MS Standard C13 and N15-labeled recombinant protein (NP_000915) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 61.4 kDa |
AA Sequence : | MELSPRSPPEMLEESDCPSPLELKS APSKKMWIKLRSLLRYMVKQLENGE INIEELKKNLEYTASLLEAVYIDET RQILDTEDELQELRSDAVPSEVRDW LASTFTQQARAKGRRAEEKPKFRSI VHAVQAGIFVERMFRRTYTSVGPTY STAVLNCLKNLDLWCFDVFSLNQAA DDHALRTIVFELLTRHNLISRFKIP TVFLMSFLDALETGYGKYKNPYHNQ IHAADVTQTVHCFLLRTGMVHCLSE IELLAIIFAAAIHDYEHTGTTNSFH IQTKSECAIVYNDRSVLENHHISSV FRLMQDDEMNIFINLTKDEFVELRA LVIEMVLATDMSCHFQQVKTMKTAL QQLERIDKPKALSLLLHAADISHPT KQWLVHSRWTKALMEEFFRQGDKEA ELGLPFSPLCDRTSTLVAQSQIGFI DFIVEPTFSVLTDVAEKSVQPLADE DSKSKNQPSFQWRQPSLDVEVGDPN PDVVSFRSTWVKRIQENKQKWKERA ASGITNQMSIDELSPCEEEAPPSPA EDEHNQNGNLDTRTRPLEQKLISEE DLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | PDE1B phosphodiesterase 1B [ Homo sapiens (human) ] |
Official Symbol : | PDE1B |
Synonyms : | PDE1B; phosphodiesterase 1B, calmodulin-dependent; PDES1B; calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase 1B; cam-PDE 1B; 63 kDa Cam-PDE; calmodulin-stimulated phosphodiesterase PDE1B1; calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase; presumed 63kDa form of the type 1 cyclic nucleotide phosphodiesterase family known as PDE1B; PDE1B1; |
Gene ID : | 5153 |
mRNA Refseq : | NM_000924 |
Protein Refseq : | NP_000915 |
MIM : | 171891 |
UniProt ID : | Q01064 |
Products Types
◆ Recombinant Protein | ||
PDE1B-6583M | Recombinant Mouse PDE1B Protein, His (Fc)-Avi-tagged | +Inquiry |
PDE1B-745H | Recombinant Human PDE1B Protein, MYC/DDK-tagged | +Inquiry |
PDE1B-042H | Recombinant Human PDE1B Protein, His/GST-tagged | +Inquiry |
PDE1B-3986R | Recombinant Rat PDE1B Protein, His (Fc)-Avi-tagged | +Inquiry |
PDE1B-1631H | Recombinant Human PDE1B Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PDE1B-627HCL | Recombinant Human PDE1B cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1825 | PDE1B Assay Kit | +Inquiry |
Kit-1827 | PDE1B TR-FRET Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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