Recombinant Human PDE1B Protein, MYC/DDK-tagged

• Cat.No.: PDE1B-745H
• Product Overview: Recombinant human PDE1B protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011]
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 61.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: phosphodiesterase 1B[ Homo sapiens ]
• Official Symbol: PDE1B
• Synonyms: PDE1B1; PDES1B
• Gene ID: 5153
• mRNA Refseq: NM_000924.3
• Protein Refseq: NP_000915
• MIM: 171891
• UniProt ID: Q01064