Recombinant Human PDE1B Protein, His/GST-tagged

Cat.No. : PDE1B-042H
Product Overview : Recombinant N-terminal His-GST-tagged full length human PDE1B1 protein (1-536) was expressed in insect cells.
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Description : The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Source : Insect cell
Species : Human
Tag : His/GST
Form : Lyophilized
Molecular Mass : 89.2 kDa
Protein length : 1-536
Endotoxin : <1.0 EU/ μg, determined by the LAL endotoxin assay.
Purity : ≥94% estimated by SDS-PAGE
Stability : ≥ 1 year
Storage : At -80 centigrade.
Storage Buffer : Sterile 50 mM Tris, pH 8.0, with 100 mM sodium chloride
SDS-PAGE: Lane 1: MW Markers<br />Lane 2: PDE1B1
Gene Name : PDE1B phosphodiesterase 1B [ Homo sapiens (human) ]
Official Symbol : PDE1B
Synonyms : PDE1B; phosphodiesterase 1B; PDE1B1; PDES1B; HEL-S-79p; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B; 63 kDa Cam-PDE; calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase; calmodulin-stimulated phosphodiesterase PDE1B1; cam-PDE 1B; epididymis secretory sperm binding protein Li 79p; phosphodiesterase 1B, calmodulin-dependent; presumed 63kDa form of the type 1 cyclic nucleotide phosphodiesterase family known as PDE1B; EC 3.1.4.17
Gene ID : 5153
mRNA Refseq : NM_000924
Protein Refseq : NP_000915
MIM : 171891
UniProt ID : Q01064

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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