Recombinant Human PDXP Protein (1-296 aa), His-tagged PDXP-2078H

Recombinant Human PDXP Protein (1-296 aa), His-tagged

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Recombinant Human PDXP Protein (1-296 aa), His-tagged

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Cat.No. : PDXP-2078H
Product Overview : Recombinant Human PDXP Protein (1-296 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Signal Transduction. Protein Description: Full Length.
Description : Protein serine phosphatase that dephosphorylates 'Ser-3' in cofilin and probably also dephosphorylates phospho-serine residues in DSTN. Regulates cofilin-dependent actin cytoskeleton reorganization. Required for normal progress through mitosis and normal cytokinesis. Does not dephosphorylate phospho-threonines in LIMK1. Does not dephosphorylate peptides containing phospho-tyrosine. Pyridoxal phosphate phosphatase. Has some activity towards pyridoxal 5'-phosphate (PLP), pyridoxine 5'-phosphate (PMP) and pyridoxine 5'-phosphate (PNP), with a highest activity with PLP followed by PNP.
Source : Yeast
Species : Human
Tag : His
Form : Tris-based buffer,50% glycerol
Molecular Mass : 33.7 kDa
Protein length : 1-296 aa
AA Sequence : MARCERLRGAALRDV LGRAQGVLFDCDGVL WNGERAVPGAPELLE RLARAGKAALFVSNN SRRARPELALRFARL GFGGLRAEQLFSSAL CAARLLRQRLPGPPD APGAVFVLGGEGLRA ELRAAGLRLAGDPSA GDGAAPRVRAVLVGY DEHFSFAKLREACAH LRDPECLLVATDRDP WHPLSDGSRTPGTGS LAAAVETASGRQALV VGKPSPYMFECITEN FSIDPARTLMVGDRL ETDILFGHRCGMTTV LTLTGVSRLEEAQAY LAAGQHDLVPHYYVE SIADLTEGLED
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with reconstitution instruction is sent along with the products.
Figure :

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Gene Name : PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase [ Homo sapiens ]
Official Symbol : PDXP
Synonyms : PDXP; dJ37E16.5; FLJ32703; chronophin; PLP phosphatase; CIN; PLP;
Gene ID : 57026
mRNA Refseq : NM_020315
Protein Refseq : NP_064711
MIM : 609246
UniProt ID : Q96GD0

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