Recombinant Mouse PDXP Protein (1-292 aa), His-tagged PDXP-2491M

Recombinant Mouse PDXP Protein (1-292 aa), His-tagged

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Recombinant Mouse PDXP Protein (1-292 aa), His-tagged

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Cat.No. : PDXP-2491M
Product Overview : Recombinant Mouse PDXP Protein (1-292 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Signal Transduction. Protein Description: Full Length.
Description : Protein serine phosphatase that dephosphorylates 'Ser-3' in cofilin and probably also dephosphorylates phospho-serine residues in DSTN. Regulates cofilin-dependent actin cytoskeleton reorganization. Required for normal progress through mitosis and normal cytokinesis (By similarity). Does not dephosphorylate phospho-threonines in LIMK1. Does not dephosphorylate peptides containing phospho-tyrosine. Pyridoxal phosphate phosphatase. Has some activity towards pyridoxal 5'-phosphate (PLP), pyridoxine 5'-phosphate (PMP) and pyridoxine 5'-phosphate (PNP), with a highest activity with PLP followed by PNP.
Source : Yeast
Species : Mouse
Tag : His
Form : Tris-based buffer,50% glycerol
Molecular Mass : 33.5 kDa
Protein length : 1-292 aa
AA Sequence : MARCERLRGAALRDV LGQAQGVLFDCDGVL WNGERIVPGAPELLQ RLARAGKNTLFVSNN SRRARPELALRFARL GFAGLRAEQLFSSAL CAARLLRQRLSGPPD ASGAVFVLGGEGLRA ELRAAGLRLAGDPGE DPRVRAVLVGYDEQF SFSRLTEACAHLRDP DCLLVATDRDPWHPL SDGSRTPGTGSLAAA VETASGRQALVVGKP SPYMFQCITEDFSVD PARTLMVGDRLETDI LFGHRCGMTTVLTLT GVSSLEEAQAYLTAG QRDLVPHYYVESIAD LMEGLED
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.
Figure :

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Gene Name : Pdxp pyridoxal (pyridoxine, vitamin B6) phosphatase [ Mus musculus ]
Official Symbol : PDXP
Synonyms : PDXP; chronophin; chronophilin; PLP phosphatase; PLP-phosophatase; PLPP; AB041662; 1600027H05Rik;
Gene ID : 57028
mRNA Refseq : NM_020271
Protein Refseq : NP_064667
UniProt ID : P60487

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