Recombinant Human PEPD Protein

• Cat.No.: PEPD-766H
• Product Overview: Recombinant Human PEPD, transcript variant 1, was expressed in E. coli.

Specification

• Description: This gene encodes a member of the peptidase family. The protein forms a homodimer that hydrolyzes dipeptides or tripeptides with C-terminal proline or hydroxyproline residues. The enzyme serves an important role in the recycling of proline, and may be rate limiting for the production of collagen. Mutations in this gene result in prolidase deficiency, which is characterized by the excretion of large amount of di- and tri-peptides containing proline. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Form: Supplied as a 0.2 µM filtered solution of PBS, pH 7.4
• Molecular Mass: 54.5kD
• AA Sequence: AAATGPSFWLGNETLKVPLALFALN RQRLCERLRKNPAVQAGSIVVLQGG EETQRYCTDTGVLFRQESFFHWAFG VTEPGCYGVIDVDTGKSTLFVPRLP ASHATWMGKIHSKEHFKEKYAVDDV QYVDEIASVLTSQKPSVLLTLRGVN TDSGSVCREASFDGISKFEVNNTIL HPEIVECRVFKTDMELEVLRYTNKI SSEAHREVMKAVKVGMKEYELESLF EHYCYSRGGMRHSSYTCICGSGENS AVLHY
• Endotoxin: Endotoxin level is <0.1 ng/µg of protein (<1EU/µg).
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining

Gene Information

• Gene Name: PEPD peptidase D [ Homo sapiens ]
• Official Symbol: PEPD
• Synonyms: PEPD; peptidase D; xaa-Pro dipeptidase; prolidase; imidodipeptidase; X-Pro dipeptidase; proline dipeptidase; aminoacyl-L-proline hydrolase; PROLIDASE; MGC10905
• Gene ID: 5184
• mRNA Refseq: NM_000285
• Protein Refseq: NP_000276
• MIM: 613230
• UniProt ID: P12955