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Recombinant Human REG3A Protein, MYC/DDK-tagged

Cat.No. : REG3A-805H
Product Overview : Recombinant human REG3A protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
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  • Gene Information
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Description : This gene encodes a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It has similarity to the C-type lectin superfamily. The enhanced expression of this gene is observed during pancreatic inflammation and liver carcinogenesis. The mature protein also functions as an antimicrobial protein with antibacterial activity. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, Nov 2014].
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass : 16.5 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : regenerating family member 3 alpha[ Homo sapiens ]
Official Symbol : REG3A
Synonyms : HIP; HIP/PAP; INGAP; PAP; PAP-H; PAP1; PBCGF; REG-III; REG3
Gene ID : 5068
mRNA Refseq : NM_002580.2
Protein Refseq : NP_002571
MIM : 167805
UniProt ID : Q06141

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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In what gastrointestinal disorders is REG3A protein implicated? 02/04/2023

REG3A has been associated with inflammatory bowel diseases (IBD), such as Crohn's disease and ulcerative colitis, where its dysregulation can contribute to inflammation and tissue damage.

In what way does REG3A impact the microbiota of the gastrointestinal tract? 08/12/2021

REG3A plays a role in maintaining the balance of the gut microbiota by influencing the composition of the microbial community.

Can REG3A be used as a biomarker for certain diseases? 07/28/2021

Yes, altered levels of REG3A have been observed in several diseases, making it a potential biomarker for gastrointestinal disorders and certain cancers.

How does REG3A function in the context of the immune response? 01/15/2021

REG3A has immunomodulatory effects, participating in the regulation of the immune response, particularly in the defense against bacterial infections.

How is REG3A being explored in cancer research? 10/14/2020

REG3A's involvement in cell growth and differentiation has led to investigations into its role in cancer, with studies exploring its potential as a therapeutic target or diagnostic marker.

Customer Reviews (3)

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Reviews
02/01/2022

    REG3A protein is of exceptional quality and is highly recommended for meeting experimental needs.

    12/16/2020

      Its purity and integrity ensure reliable and reproducible results in a wide range of applications.

      11/01/2017

        the manufacturer of REG3A protein provides excellent technical support, ensuring prompt assistance and guidance.

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