Recombinant Human TNFSF12 Protein (Asp65-Gln247), His tagged
Cat.No. : | TNFSF12-3216H |
Product Overview : | Recombinant human TNFSF12 (Asp65-Gln247) protein fused with His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | TNFSF12 is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. It is a ligand for the FN14/TWEAKR receptor. TNFSF12 has overlapping signaling functions with TNF, but displays a much wider tissue distribution. It can induce apoptosis via multiple pathways of cell death in a cell type-specific manner. It is also found that TNFSF12 promotes proliferation and migration of endothelial cells, and thus acts as a regulator of angiogenesis. TNFSF12 also is a weak inducer of apoptosis in some cell types and mediates NF-kappa-B activation. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | 21.99 kDa |
Protein Length : | Asp65-Gln247 |
Purity : | >90 % as determined by SDS-PAGE. |
Notes : | For research use only. |
Storage : | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
Storage Buffer : | Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5. |
Reconstitution : | Reconstitute in sterile water for a stock solution. |
Shipping : | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
Gene Name : | TNFSF12 tumor necrosis factor (ligand) superfamily, member 12 [ Homo sapiens (human) ] |
Official Symbol : | TNFSF12 |
Synonyms : | TNFSF12; tumor necrosis factor (ligand) superfamily, member 12; tumor necrosis factor ligand superfamily member 12; APO3L; DR3LG; TWEAK; APO3 ligand; APO3/DR3 ligand; TNF-related WEAK inducer of apoptosis; MGC20669; MGC129581; |
Gene ID : | 8742 |
mRNA Refseq : | NM_003809 |
Protein Refseq : | NP_003800 |
MIM : | 602695 |
UniProt ID : | O43508 |
Products Types
◆ Recombinant Protein | ||
Tnfsf12-86M | Active Recombinant Mouse Tnfsf12 Protein (His110-His249), C-His tagged, Animal-free, Carrier-free | +Inquiry |
TNFSF12-810M | Recombinant Mouse TNFSF12 Protein (Arg105-His249), RlgG Fc-tagged | +Inquiry |
TNFSF12-200T | Active Recombinant Human TNFSF12 Protein | +Inquiry |
TNFSF12-01H | Recombinant Human TNFSF12 Protein, His/FLAG-tagged | +Inquiry |
TNFSF12-9483M | Recombinant Mouse TNFSF12 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
TNFSF12-1155CCL | Recombinant Cynomolgus TNFSF12 cell lysate | +Inquiry |
TNFSF12-1204RCL | Recombinant Rat TNFSF12 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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