Recombinant Human WD Repeat Domain 4, T7-tagged
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Cat.No. : | WDR4-847H Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant Human WDR4 was produced in E.coli with a T7 tag at N-terminus. MW = 45490 Da (1-266 aa). |
Description : | tRNA (guanine-N(7)-)-methyltransferase subunit WDR4 is an enzyme that in humans is encoded by the WDR4 gene. This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is excluded as a candidate for a form of nonsyndromic deafness (DFNB10), but is still a candidate for other disorders mapped to 21q22.3 as well as for the development of Down syndrome phenotypes. Two transcript variants encoding the same protein have been found for this gene. |
Source : | E.coli. |
Form : | 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3. |
Purity : | 90%. |
Clonality : | N/A. |
Applications : | MS. SDS. |
Gene Name : | WDR4 WD repeat domain 4 [ Homo sapiens ] |
Synonyms : | WDR4 WD repeat domain 4; TRM82; tRNA (guanine-N(7)-)-methyltransferase subunit WDR4; WD repeat-containing protein 4 |
Gene ID : | 10785 |
mRNA Refseq : | NM_018669 |
Protein Refseq : | NP_061139 |
MIM : | 605924 |
UniProt ID : | P57081 |
Chromosome Location : | 21q22.3 |
Function : | protein binding; contributes_to tRNA (guanine-N7-)-methyltransferase activity |
◆ Recombinant Protein
Wdr4-6979M | Recombinant Mouse Wdr4 Protein, Myc/DDK-tagged | +Inquiry |
WDR4-6738Z | Recombinant Zebrafish WDR4 | +Inquiry |
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◆ Lysates
WDR4-348HCL | Recombinant Human WDR4 293 Cell Lysate | +Inquiry |
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WDR4WDR5WDR6WDR20WDR61WDR77WDR13WDR36WDR42AWDR79WDR41WDR45LWDR87WDR88WDR89WDR18WDR70WDR73WDR74WDR75WDR76WDR46WDR49WDR26WDR27WDR3WDR19WDR31WDR33WDR35WDR37WDR44WDR45WDR54WDR59WDR5BWDR62WDR65WDR66WDR11WDR12WDR16WDR1WDR78WDR8WDR85WDR86WDR91WDR53WDR92WDR17WDR24WDR25WDR43WDR47WDR48WDR60WDR63WDR64WDR69Wdr20aWDR52WDR81WDR83OSWDR83WDR90WDR93WDR82Wdr95Wdr20bWdr25lWDR34Wdr35lWdr38Wdr55Wdr67Wdr7Wdr72Wdr96
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