Recombinant Mouse Ccl22 protein
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Cat.No. : | Ccl22-91M Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant Mouse Ccl22 protein was expressed in Escherichia coli. |
Description : | CCL22 is a protein that in mouse is encoded by the CCL22 gene, which locates on the Chr. 8. It is highly expressed in macrophage, monocyte-derived dendritic cell and thymus, additionally, also detected in the tissues of thymus, lymph node and appendix. CCL22 can bind to CCR4, and is a chemoattractant for monocytes, monocyte-derived dendritic cells, and natural killer cells, but not for neutrophils, eosinophils, and resting T-lymphocytes. After secreted from monocyte-derived dendritic cells, the protein can be proteolytic cleaved into three forms: MDC (3-69), MDC (5-69), MDC (7-69). |
Source : | E.coli |
Species : | Mouse |
Form : | Lyophilized from a 0.2μm filtered concentrated solution in 20 mM PB, pH 7.4, 150 mM NaCl. |
Bio-activity : | Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human activated lymphocytes is in a concentration range of 10-100 ng/ml. |
Molecular Mass : | Approximately 7.8 kDa, a single, non-glycosylated polypeptide chain containing 68 amino acids. |
Protein length : | 68 |
AA Sequence : | GPYGANVEDS ICCQDYIRHP LPSRLVKEFF WTSKSCRKPG VVLITVKNRD ICADPRQVWV KKLLHKLS |
Endotoxin : | Less than 1 EU/μg of rMuMDC/CCL22 as determined by LAL method. |
Purity : | >97% by SDS-PAGE and HPLC analysis. |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Reconstitution : | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤-20 centigrade. Further dilutions should be made in appropriate buffered solutions. |
SDS-PAGE of Ccl22-91M : |
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Gene Name : | Ccl22 |
Official Symbol : | Ccl22 |
Synonyms : | CCL22; chemokine (C-C motif) ligand 22; C-C motif chemokine 22; CC chemokine ABCD-1; small-inducible cytokine A22; activated B and dendritic cell-derived; small inducible cytokine subfamily A22; dendritic cell and B cell derived chemokine; small inducible cytokine subfamily A, member 22; SMALL INDUCIBLE CYTOKINE A22 PRECURSOR (CC CHEMOKINE ABCD-1) (ACTIVATED B AND DENDRITIC CELL-DERIVED); MDC; DCBCK; ABCD-1; Scya22; |
Gene ID : | 20299 |
mRNA Refseq : | NM_009137 |
Protein Refseq : | NP_033163 |
UniProt ID : | O88430 |
◆ Recombinant Protein
CCL22-1108P | Recombinant Pig CCL22 Protein, His-tagged | +Inquiry |
CCL22-0627H | Recombinant Human CCL22 Protein, GST-Tagged | +Inquiry |
CCL22-2884M | Recombinant Mouse CCL22 Protein | +Inquiry |
CCL22-311H | Recombinant Human CCL22 Protein, His-tagged | +Inquiry |
Ccl22-131M | Recombinant Mouse Ccl22 Protein | +Inquiry |
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◆ Lysates
CCL22-7728HCL | Recombinant Human CCL22 293 Cell Lysate | +Inquiry |
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CCL1CCL11Ccl12CCL13CCL14CCL15CCL16CCL17CCL18CCL19CCL2CCL20CCL21Ccl21cCCL22CCL23CCL24CCL25CCL26CCL27Ccl27aCCL28CCL3CCL3L1Ccl4CCL5Ccl6CCL7CCL8Ccl9CCL4L2Ccl21aCCL4L1CCL3L3Ccl21bCcl27b
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