Recombinant Mouse Cryab Protein, Myc/DDK-tagged

Cat.No. : Cryab-2326M
Product Overview : Purified recombinant protein of mouse full-length crystallin, alpha B (Cryab), with C-terminal MYC/DDK tag, expressed in HEK293T cells.
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Description : This gene encodes a member of the small heat-shock protein (HSP20) family. The encoded protein is a molecular chaperone that protects proteins against thermal denaturation and other stresses. This protein is a component of the eye lens, regulates lens differentiation and functions as a refractive element in the lens. This protein is a negative regulator of inflammation, has anti-apoptotic properties and also plays a role in the formation of muscular tissue. Mice lacking this gene exhibit worse experimental autoimmune encephalomyelitis and inflammation of the central nervous system compared to the wild type. In mouse models, this gene has a critical role in alleviating the pathology of the neurodegenerative Alexander disease. Mutations in the human gene are associated with myofibrillar myopathy 2, fatal infantile hypertonic myofibrillar myopathy, multiple types of cataract and dilated cardiomyopathy. Alternative splicing results in multiple transcript variants.
Source : HEK293T
Species : Mouse
Tag : Myc/DDK
Molecular Mass : 20.1 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Storage : Store at -80 centigrade after receiving vials.
Concentration : >50 μg/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : Cryab crystallin, alpha B [ Mus musculus (house mouse) ]
Official Symbol : Cryab
Synonyms : CRYAB; crystallin, alpha B; alpha-crystallin B chain; P23; alpha B-crystallin; alpha(B)-crystallin; crystallin, alpha 2; Crya2; HspB5; Crya-2
Gene ID : 12955
mRNA Refseq : NM_009964
Protein Refseq : NP_034094
UniProt ID : P23927

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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