Recombinant Mouse Efnb2 Protein, His-tagged
Cat.No. : | Efnb2-367M |
Product Overview : | Recombinant mouse EFNB2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | EFNB2, also known as ephrin-B2, is cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. It binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. It may play a role in constraining the orientation of longitudinally projecting axons. |
Source : | Insect cell |
Species : | Mouse |
Tag : | His |
Form : | Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
Molecular Mass : | 23.4kDa (212aa)28-40KDa (SDS-PAGE under reducing conditions.) |
AA Sequence : | RSIVLEPIYW NSSNSKFLPG QGLVLYPQIG DKLDIICPKV DSKTVGQYEY YKVYMVDKDQ ADRCTIKKEN TPLLNCARPD QDVKFTIKFQEFSPNLWGLE FQKNKDYYII STSNGSLEGL DNQEGGVCQT RAMKILMKVG QDASSAGSAR NHGPTRRPEL EAGTNGRSST TSPFVKPNPGSSTDGNSAGH SGNNLLGSEV ALFALEHHHH HH |
Endotoxin : | < 1.0 EU per 1 microgram of protein (determined by LAL method) |
Purity : | >90% by SDS - PAGE |
Storage : | Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5mg/ml (determined by Absorbance at 280nm) |
Gene Name : | Efnb2 ephrin B2 [ Mus musculus ] |
Official Symbol : | Efnb2 |
Synonyms : | EFNB2; ephrin B2; ephrin-B2; HTK ligand; EPH-related receptor tyrosine kinase ligand 5; Epl5; ELF-2; Eplg5; Htk-L; Lerk5; LERK-5; NLERK-1; |
Gene ID : | 13642 |
mRNA Refseq : | NM_010111 |
Protein Refseq : | NP_034241 |
MIM : | |
UniProt ID : | |
Pathway : | Axon guidance, organism-specific biosystem; Axon guidance, conserved biosystem; |
Function : | ephrin receptor binding; protein binding; receptor binding; |
Products Types
◆ Recombinant Protein | ||
EFNB2-3104H | Recombinant Human EFNB2 Protein, GST-tagged | +Inquiry |
Efnb2-1408M | Recombinant Mouse Efnb2 Protein, His&GST-tagged | +Inquiry |
EFNB2-2836H | Recombinant Human EFNB2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Efnb2-131M | Recombinant Mouse Efnb2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Efnb2-896M | Recombinant Mouse Efnb2 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
EFNB2-1540RCL | Recombinant Rat EFNB2 cell lysate | +Inquiry |
EFNB2-2405MCL | Recombinant Mouse EFNB2 cell lysate | +Inquiry |
EFNB2-936HCL | Recombinant Human EFNB2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionEphB6 overexpression up-regulates the expression of its ligand EFNB2.
EFNB2 is associated with breast, colon, bladder, cervical and other cancers.
EFNB2 is involved in tissue plasticity, tumorigenesis, and other biological processes.
EFNB2 is widely expressed in tumor vasculature.
EFNB2 promotes BUC cell proliferation by inhibiting apoptosis in BUC cells.
EFNB2 is one of the physiological ligands of EphB6 that functions by binding to EphB6.
Customer Reviews (3)
Write a reviewDuring the experiment, the technician helped me solve the problems in a timely and accurate manner.
The EFNB2 proteins purchased from your company is suitable for WB.
Received high quality protein products and obtained satisfactory experimental results.
Ask a Question for All Efnb2 Products
Required fields are marked with *
My Review for All Efnb2 Products
Required fields are marked with *
Inquiry Basket