Recombinant Mouse Il10 Protein
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| Cat.No. : | Il10-083M |
| Product Overview : | Purified recombinant protein of Mouse interleukin 10 (Il10) (Ser19-Ser178) without tag was expressed in E.coli. |
| Description : | This gene encodes an anti-inflammatory cytokine that is a member of the class-2 cytokine family. The encoded protein is secreted by cells of both the innate and adaptive immune systems and is crucial for limiting the immune response to a broad range of pathogens. It also has been shown to suppress autoimmune responses. This protein mediates it's immunosuppressive signal through a specific interleukin 10 receptor complex. Aberrant functioning of this gene is associated with numerous immune disorders including graft-versus-host disease, and increased susceptibility to HIV-1 infection and rheumatoid arthritis. |
| Source : | E. coli |
| Species : | Mouse |
| Bio-activity : | The ED50 is 1- 2 ng/ml, corresponding to a specific activity of 1- 0.5 x 10^6 units/mg, determined by the dose dependent stimulation MC/9 cell proliferation. |
| Molecular Mass : | 18.9 kDa |
| Endotoxin : | Less than 0.01 ng per µg protein as determined by the LAL method |
| Purity : | >98%, as determined by Coomassie stained SDS-PAGE. |
| Stability : | Unopened vial can be stored between 2 centigrade and 8 centigrade for up to 2 weeks, at -20 centigrade for up to 6 months, or at -70 centigrade or below until the expiration date. Aliquots can be stored between 2 centigrade and 8 centigrade for up to one week and stored at -20 centigrade or colder for up to 3 months. Avoid repeated freeze/thaw cycles. |
| Storage : | Store at -80 centigrade. |
| Concentration : | Protein formulated and vialed at >50 ug/mL in specified buffer |
| Storage Buffer : | 20mM Tris pH7.5 |
| Figure : |
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| Gene Name : | Il10 interleukin 10 [ Mus musculus (house mouse) ] |
| Official Symbol : | Il10 |
| Synonyms : | Il10; interleukin 10; CSIF; Il-10; interleukin-10; cytokine synthesis inhibitory factor |
| Gene ID : | 16153 |
| mRNA Refseq : | NM_010548 |
| Protein Refseq : | NP_034678 |
| UniProt ID : | P18893 |
◆ Recombinant Protein
| IL10-20R | Recombinant Rhesus monkey IL10 protein, His-tagged | +Inquiry |
| Il10-084M | Recombinant Mouse Il10 Protein, MYC/DDK-tagged | +Inquiry |
| Il10-082M | Recombinant Mouse Il10 Protein | +Inquiry |
| IL10-2033H | Recombinant Human IL10 Protein, His-tagged | +Inquiry |
| IL10-4400M | Recombinant Monkey IL10 Protein | +Inquiry |
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◆ Lysates
| IL10-2079HCL | Recombinant Human IL10 cell lysate | +Inquiry |
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IL10IL10RAIL10RBIL11IL11RAIl11ra1IL12IL12AIL12BIL12RB1IL13IL13RA1IL13RA2IL15IL15RAIL16IL17AIL17BIl17cIL17DIl17fIL17RAIL17RDIL18IL18BPIL18R1IL18RAPIl19Il1aIl1bIL1F10IL1R1Il1r2IL1RAPIL1RAPL1IL1RAPL2IL1RL1IL1RL2Il1rnIL2Il20IL20RAIL21IL21RIL22IL22BPIL22RA1IL22RA2IL23AIL24Il25IL27IL27RAIL28AIl28bIL29IL2RAIL2RBIl2rgIL3IL31IL32Il33Il34IL3RAIL4IL4RIl4raIl5IL5RAIl6IL6RIl6raIL6STIl7IL7RIL8IL9IL36AIl12rb2IL17RBIL23RIL26IL31RAIL36BIL36GIL36RNIL37IL9RIL17RCIL17REIL28RAIL4I1IL20RBIL17RELIl11ra2IL27bIL7RAIl23a&Il12b
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