Recombinant Mouse Il17a Protein Il17a-095M

Recombinant Mouse Il17a Protein


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Recombinant Mouse Il17a Protein

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Cat.No. : Il17a-095M
Product Overview : Purified recombinant protein of Mouse IL-17A, the region of Ala26-Ala158, from gene Accession# NM_010552 and mouse IL-17F, the region of Arg29-Ala161, from gene Accession# NM_145856 without tag was expressed in E.coli.
Description : This gene encodes a pro-inflammatory cytokine that is a member of the interleukin-17 family. The encoded protein plays a central role in host defense against diverse pathogens. The encoded protein is produced by activated T-cells and certain cell types of innate immune system. The active protein functions as either a homodimer with other interleukin-17 family members and signals through the interleukin-17 receptor to induce inflammatory cytokine production. Aberrant expression of this gene is associated with autoinflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Source : E. coli
Species : Mouse
Bio-activity : The ED50 is 125 - 175 ng/ml, corresponding to a specific activity 0.57 - 0.8 x 10^4 units/mg, determined by a dose dependent stimulation of fetal mouse skin fibroblasts production of IL-6.
Molecular Mass : 30 kDa
Endotoxin : Less than 0.1 EU/µg (<0.01 ng/µg) protein as determined by the LAL method
Purity : >98%, as determined by Coomassie stained SDS-PAGE.
Stability : Unopened vial can be stored between 2 centigrade and 8 centigrade for up to 2 weeks, at -20 centigrade for up to 6 months, or at -70 centigrade or below until the expiration date. Aliquots can be stored between 2 centigrade and 8 centigrade for up to one week and stored at -20 centigrade or colder for up to 3 months. Avoid repeated freeze/thaw cycles.
Storage : Store at -80 centigrade.
Concentration : Protein formulated and vialed at >50 ug/mL in specified buffer
Storage Buffer : 10 mM NaH2PO4, 0.15 M NaCl, pH7.2
Figure :

Gene Name : Il17a interleukin 17A [ Mus musculus (house mouse) ]
Official Symbol : Il17a
Synonyms : Il17a; interleukin 17A; Il17; Ctla8; IL-17; Ctla-8; IL-17A; interleukin-17A; cytotoxic T-lymphocyte-associated antigen 8
Gene ID : 16171
mRNA Refseq : NM_010552
Protein Refseq : NP_034682
UniProt ID : Q62386

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