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Recombinant Mouse Il17a Protein
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| Cat.No. : | Il17a-095M |
| Product Overview : | Purified recombinant protein of Mouse IL-17A, the region of Ala26-Ala158, from gene Accession# NM_010552 and mouse IL-17F, the region of Arg29-Ala161, from gene Accession# NM_145856 without tag was expressed in E.coli. |
| Description : | This gene encodes a pro-inflammatory cytokine that is a member of the interleukin-17 family. The encoded protein plays a central role in host defense against diverse pathogens. The encoded protein is produced by activated T-cells and certain cell types of innate immune system. The active protein functions as either a homodimer with other interleukin-17 family members and signals through the interleukin-17 receptor to induce inflammatory cytokine production. Aberrant expression of this gene is associated with autoinflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. |
| Source : | E. coli |
| Species : | Mouse |
| Bio-activity : | The ED50 is 125 - 175 ng/ml, corresponding to a specific activity 0.57 - 0.8 x 10^4 units/mg, determined by a dose dependent stimulation of fetal mouse skin fibroblasts production of IL-6. |
| Molecular Mass : | 30 kDa |
| Endotoxin : | Less than 0.1 EU/µg (<0.01 ng/µg) protein as determined by the LAL method |
| Purity : | >98%, as determined by Coomassie stained SDS-PAGE. |
| Stability : | Unopened vial can be stored between 2 centigrade and 8 centigrade for up to 2 weeks, at -20 centigrade for up to 6 months, or at -70 centigrade or below until the expiration date. Aliquots can be stored between 2 centigrade and 8 centigrade for up to one week and stored at -20 centigrade or colder for up to 3 months. Avoid repeated freeze/thaw cycles. |
| Storage : | Store at -80 centigrade. |
| Concentration : | Protein formulated and vialed at >50 ug/mL in specified buffer |
| Storage Buffer : | 10 mM NaH2PO4, 0.15 M NaCl, pH7.2 |
| Figure : |
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| Gene Name : | Il17a interleukin 17A [ Mus musculus (house mouse) ] |
| Official Symbol : | Il17a |
| Synonyms : | Il17a; interleukin 17A; Il17; Ctla8; IL-17; Ctla-8; IL-17A; interleukin-17A; cytotoxic T-lymphocyte-associated antigen 8 |
| Gene ID : | 16171 |
| mRNA Refseq : | NM_010552 |
| Protein Refseq : | NP_034682 |
| UniProt ID : | Q62386 |
◆ Recombinant Protein
| Il17a-094M | Recombinant Mouse Il17a Protein | +Inquiry |
| IL17A-848M | Recombinant Mouse IL17A Protein (Ala26-Ala158) | +Inquiry |
| Il17a-096M | Recombinant Mouse Il17a Protein, MYC/DDK-tagged | +Inquiry |
| IL17A-001C | Recombinant Cynomolgus Monkey IL17A Protein | +Inquiry |
| IL17A-547H | Recombinant Human IL17A Protein (Ile20-Ala155), Met, Biotinylated | +Inquiry |
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◆ Lysates
| IL17A-001HCL | Recombinant Human IL17A cell lysate | +Inquiry |
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IL10IL10RAIL10RBIL11IL11RAIl11ra1IL12IL12AIL12BIL12RB1IL13IL13RA1IL13RA2IL15IL15RAIL16IL17AIL17BIl17cIL17DIl17fIL17RAIL17RDIL18IL18BPIL18R1IL18RAPIl19Il1aIl1bIL1F10IL1R1Il1r2IL1RAPIL1RAPL1IL1RAPL2IL1RL1IL1RL2Il1rnIL2Il20IL20RAIL21IL21RIL22IL22BPIL22RA1IL22RA2IL23AIL24Il25IL27IL27RAIL28AIl28bIL29IL2RAIL2RBIl2rgIL3IL31IL32Il33Il34IL3RAIL4IL4RIl4raIl5IL5RAIl6IL6RIl6raIL6STIl7IL7RIL8IL9IL36AIl12rb2IL17RBIL23RIL26IL31RAIL36BIL36GIL36RNIL37IL9RIL17RCIL17REIL28RAIL4I1IL20RBIL17RELIl11ra2IL27bIL7RAIl23a&Il12b
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