Active Recombinant Mouse Il17a Protein
Cat.No. : | Il17a-095M |
Product Overview : | Purified recombinant protein of Mouse IL-17A, the region of Ala26-Ala158, from gene Accession# NM_010552 and mouse IL-17F, the region of Arg29-Ala161, from gene Accession# NM_145856 without tag was expressed in E.coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a pro-inflammatory cytokine that is a member of the interleukin-17 family. The encoded protein plays a central role in host defense against diverse pathogens. The encoded protein is produced by activated T-cells and certain cell types of innate immune system. The active protein functions as either a homodimer with other interleukin-17 family members and signals through the interleukin-17 receptor to induce inflammatory cytokine production. Aberrant expression of this gene is associated with autoinflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. |
Source : | E. coli |
Species : | Mouse |
Bio-activity : | The ED50 is 125 - 175 ng/ml, corresponding to a specific activity 0.57 - 0.8 x 10^4 units/mg, determined by a dose dependent stimulation of fetal mouse skin fibroblasts production of IL-6. |
Molecular Mass : | 30 kDa |
Endotoxin : | Less than 0.1 EU/µg (<0.01 ng/µg) protein as determined by the LAL method |
Purity : | >98%, as determined by Coomassie stained SDS-PAGE. |
Stability : | Unopened vial can be stored between 2 centigrade and 8 centigrade for up to 2 weeks, at -20 centigrade for up to 6 months, or at -70 centigrade or below until the expiration date. Aliquots can be stored between 2 centigrade and 8 centigrade for up to one week and stored at -20 centigrade or colder for up to 3 months. Avoid repeated freeze/thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | Protein formulated and vialed at >50 ug/mL in specified buffer |
Storage Buffer : | 10 mM NaH2PO4, 0.15 M NaCl, pH7.2 |
Gene Name : | Il17a interleukin 17A [ Mus musculus (house mouse) ] |
Official Symbol : | Il17a |
Synonyms : | Il17a; interleukin 17A; Il17; Ctla8; IL-17; Ctla-8; IL-17A; interleukin-17A; cytotoxic T-lymphocyte-associated antigen 8 |
Gene ID : | 16171 |
mRNA Refseq : | NM_010552 |
Protein Refseq : | NP_034682 |
UniProt ID : | Q62386 |
Products Types
◆ Recombinant Protein | ||
IL17a-0022H | Recombinant Human IL17a Protein | +Inquiry |
IL17A-182H | Active Recombinant Human IL17A Protein (Ile20-Ala155), C-His tagged, Animal-free, Carrier-free | +Inquiry |
IL17A-001C | Recombinant Cynomolgus Monkey IL17A Protein | +Inquiry |
Il17a-149M | Recombinant Active Mouse IL17A Protein, His-tagged(C-ter) | +Inquiry |
IL17A-48H | Recombinant Human IL17A Protein | +Inquiry |
◆ Lysates | ||
IL17A-001HCL | Recombinant Human IL17A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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