Recombinant Mouse Il17b, Fc-tagged
Cat.No. : | Il17b-513M |
Product Overview : | A DNA sequence encoding the mouse IL17B (NP_062381.1) (Met1-Phe180) was expressed with the Fc region of human IgG1 at the C-terminus. |
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Source : | Baculovirus-Insect cells |
Species : | Mouse |
Tag : | Fc |
Form : | Lyophilized from sterile PBS, pH7.4. |
Molecular Mass : | The recombinant mouse IL17B/Fc is a disulfide-linked homodimer. The reduced monomer comprises 396 amino acids and has a predicted molecular mass of 44.5 kDa. The apparent molecular mass of the protein is approximately 57 kDa in SDS-PAGE under reducing conditions. |
Protein length : | Met1-Phe180 |
Endotoxin : | < 1.0 eu per μg of the protein as determined by the LAL method. |
Purity : | >90 % as determined by SDS-PAGE |
Stability : | Samples are stable for up to twelve months from date of receipt at -70℃ |
Storage : | Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | Hardcopy of COA with reconstitution instruction is sent along with the products. |
Gene Name : | Il17b interleukin 17B [ Mus musculus ] |
Official Symbol : | Il17b |
Synonyms : | IL17B; interleukin 17B; interleukin-17B; IL-17B; cytokine CX1; cytokine-like protein ZCYTO7; gene for cytokine-like protein; neuronal interleukin-17-related factor; Zcyto7; 1110006O16Rik; 1700006N07Rik; |
Gene ID : | 56069 |
mRNA Refseq : | NM_019508 |
Protein Refseq : | NP_062381 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; |
Function : | cytokine activity; receptor binding; |
Products Types
◆ Lysates | ||
IL17B-5244HCL | Recombinant Human IL17B 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionCo-culture experiments and signaling pathway analysis reveal IL17B's interaction with other cytokines.
Techniques like surface plasmon resonance elucidate IL17B's binding to its receptor.
In vivo models combine IL17B overexpression or neutralization with tumor models to study its role.
Human tissue samples are analyzed using immunohistochemistry and cytokine profiling to understand IL17B's effects.
Flow cytometry and functional assays explore how IL17B affects immune cell activation and cytokine production.
Research uses animal models and biomarker analysis to study IL17B in neuroinflammatory diseases.
Genetic techniques like CRISPR/Cas9 knockout or siRNA knockdown validate IL17B's functional impact.
Transwell assays and impedance-based methods evaluate IL17B's impact on endothelial barrier integrity.
Western blotting and phosphorylation assays uncover IL17B's downstream signaling pathways.
Gene expression analysis involves qPCR or RNA sequencing to distinguish IL17B expression patterns.
Customer Reviews (3)
Write a reviewSuitable for signaling studies.
High solubility
Potent in B-cell assays.
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