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Active Recombinant Mouse Il21 Protein

Cat.No. : Il21-10M
Product Overview : Recombinant mouse IL-21 (18-146aa) without tag was expressed in E. coli and purified by using conventional chromatography techniques.
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  • Gene Information
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Description : Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG1 and IgG3 in B-cells
Source : E.coli
Species : Mouse
Form : Liquid
Bio-activity : The activity is determined by the IFN-g ELISA in a using NK-92 human natural killer cells. The ED50 range ≤ 100 ng/mL.
Molecular Mass : 15 kDa confirmed by MALDI-TOF
Identity : 130aa
AA Sequence : MHKSSPQGPDRLLIRLRHLIDIVEQ LKIYENDLDPELLSAPQDVKGHCEH AAFACFQKAKLKPSNPGNNKTFIID LVAQLRRRLPARRGGKKQKHIAKCP SCDSYEKRTPKEFLERLKWLLQKMI HQHLS
Endotoxin : < 1 EU/μg of protein (determined by LAL method)
Purity : > 90% by SDS-PAGE
Applications : SDS-PAGE, Bioactivity
Storage : Can be stored at 2 to 8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 1 mg/mL (determined by Bradford assay)
Storage Buffer : Phosphate-Buffered Saline (pH 7.4)
Gene Name : Il21 interleukin 21 [ Mus musculus (house mouse) ]
Official Symbol : Il21
Synonyms : Il21; interleukin 21; IL-21; interleukin-21
Gene ID : 60505
mRNA Refseq : NM_021782
Protein Refseq : NP_068554
UniProt ID : Q9ES17

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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In which types of cancer has IL21 protein shown promising results? 02/17/2023

IL21 has demonstrated efficacy in preclinical and clinical studies for various cancers, including melanoma, renal cell carcinoma, and lymphoma.

Are there any side effects associated with IL21 therapy? 11/12/2021

Common side effects may include fatigue, fever, and flu-like symptoms. However, the severity and type of side effects can vary among individuals.

Can IL21 be used as a standalone treatment for cancer? 09/17/2021

IL21 is often investigated in combination with other cancer therapies to enhance its effectiveness, and it has shown promise in combination treatments.

Are there any ongoing clinical trials exploring the use of IL21 in autoimmune conditions? 03/04/2020

Yes, several clinical trials are investigating the efficacy and safety of IL21 in autoimmune diseases, such as rheumatoid arthritis and lupus.

How does IL21 influence the development of memory T cells? 10/29/2018

IL21 promotes the differentiation and survival of memory T cells, contributing to the long-term immune response against pathogens.

Customer Reviews (3)

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Reviews
08/19/2022

    With the IL21 protein at hand, I am excited to embark on my scientific journey with confidence and optimism.

    01/30/2022

      I am confident that incorporating the IL21 protein into my research will yield accurate and reliable results, enabling deeper insights into cellular processes

      04/23/2019

        Their expertise and guidance will undoubtedly prove valuable in overcoming hurdles and maximizing the potential of this protein in my research endeavors.

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