Active Recombinant Mouse Il21 Protein
Cat.No. : | Il21-10M |
Product Overview : | Recombinant mouse IL-21 (18-146aa) without tag was expressed in E. coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG1 and IgG3 in B-cells |
Source : | E.coli |
Species : | Mouse |
Form : | Liquid |
Bio-activity : | The activity is determined by the IFN-g ELISA in a using NK-92 human natural killer cells. The ED50 range ≤ 100 ng/mL. |
Molecular Mass : | 15 kDa confirmed by MALDI-TOF |
Identity : | 130aa |
AA Sequence : | MHKSSPQGPDRLLIRLRHLIDIVEQ LKIYENDLDPELLSAPQDVKGHCEH AAFACFQKAKLKPSNPGNNKTFIID LVAQLRRRLPARRGGKKQKHIAKCP SCDSYEKRTPKEFLERLKWLLQKMI HQHLS |
Endotoxin : | < 1 EU/μg of protein (determined by LAL method) |
Purity : | > 90% by SDS-PAGE |
Applications : | SDS-PAGE, Bioactivity |
Storage : | Can be stored at 2 to 8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -80 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/mL (determined by Bradford assay) |
Storage Buffer : | Phosphate-Buffered Saline (pH 7.4) |
Gene Name : | Il21 interleukin 21 [ Mus musculus (house mouse) ] |
Official Symbol : | Il21 |
Synonyms : | Il21; interleukin 21; IL-21; interleukin-21 |
Gene ID : | 60505 |
mRNA Refseq : | NM_021782 |
Protein Refseq : | NP_068554 |
UniProt ID : | Q9ES17 |
Products Types
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Il21-1672R | Recombinant Rat Il21 Protein, His-tagged | +Inquiry |
IL21-174H | Recombinant Active Human IL21 Protein, His-tagged(C-ter) | +Inquiry |
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◆ Lysates | ||
IL21-001RCL | Recombinant Rat IL21 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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Q&As (5)
Ask a questionIL21 has demonstrated efficacy in preclinical and clinical studies for various cancers, including melanoma, renal cell carcinoma, and lymphoma.
Common side effects may include fatigue, fever, and flu-like symptoms. However, the severity and type of side effects can vary among individuals.
IL21 is often investigated in combination with other cancer therapies to enhance its effectiveness, and it has shown promise in combination treatments.
Yes, several clinical trials are investigating the efficacy and safety of IL21 in autoimmune diseases, such as rheumatoid arthritis and lupus.
IL21 promotes the differentiation and survival of memory T cells, contributing to the long-term immune response against pathogens.
Customer Reviews (3)
Write a reviewWith the IL21 protein at hand, I am excited to embark on my scientific journey with confidence and optimism.
I am confident that incorporating the IL21 protein into my research will yield accurate and reliable results, enabling deeper insights into cellular processes
Their expertise and guidance will undoubtedly prove valuable in overcoming hurdles and maximizing the potential of this protein in my research endeavors.
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