Recombinant Human IL21 Protein (Leu23-Ser162), C-His tagged

• Cat.No.: IL21-2926H
• Product Overview: Recombinant human IL21 (Leu23-Ser162) protein fused with the C-His tag was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: His
• Molecular Mass: 17.46 kDa
• Protein length: Leu23-Ser162
• Purity: >90 % as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: 0.01M PBS, pH 7.4, 0.02 % NLS
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: IL21 interleukin 21 [ Homo sapiens (human) ]
• Official Symbol: IL21
• Synonyms: IL21; interleukin 21; interleukin-21; IL 21; Za11; interleukin-21 isoform; IL-21
• Gene ID: 59067
• mRNA Refseq: NM_001207006
• Protein Refseq: NP_001193935
• MIM: 605384
• UniProt ID: Q9HBE4

Reviews

08/19/2022

With the IL21 protein at hand, I am excited to embark on my scientific journey with confidence and optimism.

01/30/2022

I am confident that incorporating the IL21 protein into my research will yield accurate and reliable results, enabling deeper insights into cellular processes

04/23/2019

Their expertise and guidance will undoubtedly prove valuable in overcoming hurdles and maximizing the potential of this protein in my research endeavors.

Q&As

In which types of cancer has IL21 protein shown promising results?

IL21 has demonstrated efficacy in preclinical and clinical studies for various cancers, including melanoma, renal cell carcinoma, and lymphoma.

Are there any side effects associated with IL21 therapy?

Common side effects may include fatigue, fever, and flu-like symptoms. However, the severity and type of side effects can vary among individuals.

Can IL21 be used as a standalone treatment for cancer?

IL21 is often investigated in combination with other cancer therapies to enhance its effectiveness, and it has shown promise in combination treatments.

Are there any ongoing clinical trials exploring the use of IL21 in autoimmune conditions?

Yes, several clinical trials are investigating the efficacy and safety of IL21 in autoimmune diseases, such as rheumatoid arthritis and lupus.

How does IL21 influence the development of memory T cells?

IL21 promotes the differentiation and survival of memory T cells, contributing to the long-term immune response against pathogens.