Recombinant Rat Cd59 protein(Met1-Asn100), hFc-tagged
Cat.No. : | Cd59-8764R |
Product Overview : | Recombinant Rat CD59 (P27274) (Met1-Asn100) was expressed in HEK293, fused with the Fc region of Human IgG1 at the C-terminus. |
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Source : | HEK293 |
Species : | Rat |
Tag : | Fc |
Protein length : | Met1-Asn100 |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Molecular Mass : | The recombinant rat CD59 /Fc is a disulfide-linked homodimer. The reduced monomer comprises 319 amino acids and has a predicted molecular mass of 35.8 kDa. The apparent molecular mass of the protein is approximately 40 and 43 kDa in SDS-PAGE under reducing conditions. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 85 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | Cd59 CD59 molecule, complement regulatory protein [ Rattus norvegicus ] |
Official Symbol : | Cd59 |
Synonyms : | CD59; CD59 molecule, complement regulatory protein; CD59 glycoprotein; protectin; CD59 antigen; Cb59b molecule; MAC-inhibitory protein; membrane attack complex inhibition factor; CD59b moleucle, complement regulatory protein; Cd59a; Cd59b; MACIF; MACIP; MAC-IP; |
Gene ID : | 25407 |
mRNA Refseq : | NM_012925 |
Protein Refseq : | NP_037057 |
Products Types
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CD59-692H | Recombinant Human CD59 Protein, His and C-hFc-tagged | +Inquiry |
CD59-918R | Recombinant Rat CD59 Protein, His (Fc)-Avi-tagged | +Inquiry |
CD59-202H | Recombinant Human CD59 Protein, C-His-tagged | +Inquiry |
◆ Lysates | ||
CD59-1019CCL | Recombinant Cynomolgus CD59 cell lysate | +Inquiry |
CD59-1365RCL | Recombinant Rat CD59 cell lysate | +Inquiry |
CD59-1968HCL | Recombinant Human CD59 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewThe quality is very high and the reliability is very helpful for our research results.
There are no doping impurities, the experimental effect is very good, and I will recommend it to other students.
Easy to operate and cost-effective.
Q&As (6)
Ask a questionIn hemolytic diseases, the deficiency or dysfunction of CD59 may lead to excessive lysis of red blood cells because the formation of the complement C5b-9 complex cannot be effectively prevented.
Yes, the expression level of CD59 can vary in different cell types. In general, it is expressed higher in blood cells and some tumor cells.
When researching CD59, laboratories may encounter technical challenges such as selecting the appropriate assay, ensuring the quality and consistency of samples, and the complexity of interpreting results. In addition, CD59 expression variations in different cell types and experimental conditions need to be considered.
Aberrant expression of CD59 has been associated with a variety of diseases, including but not limited to hemolytic diseases, certain types of cancer, and autoimmune diseases.
CD59 expression can be detected using flow cytometry, immunofluorescence staining, or western blotting.
The current treatment for CD59 is still in the research stage, and there is no drug approved for clinical use. However, some studies are exploring the use of gene therapy or antibody therapy to modulate CD59 expression or function.
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