Recombinant Rat IL9R Protein, His-tagged
|Product Overview :||Recombinant rat IL9R / Interleukin 9 receptor (EDM04022.1) extracellular domain (Met 1-Ala 270) was expressed, fused with a polyhistidine tag at the C-terminus.|
- Gene Information
- Related Products
|Predicted N Terminal :||Val 38|
|Form :||Lyophilized from sterile PBS, pH 7.4, 5%~8% trehalose and mannitol.|
|Molecular Mass :||The recombinant rat IL9R / Interleukin 9 receptor comprises 244 amino acids and predicts a molecular mass of 28.2 kDa. The apparent molecular mass of the rat IL9R / Interleukin 9 receptor is approximately 36 kDa in SDS-PAGE under reducing conditions due to glycosylation.|
|Endotoxin :||< 1.0 EU per μg of the protein as determined by the LAL method.|
|Purity :||>90 % as determined by SDS-PAGE.|
|Stability :||Samples are stable for up to twelve months from date of receipt at -70ºC.|
|Storage :||Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.|
|Reconstitution :||It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4ºC before opening to recover the entire contents.|
|Gene Name :||Il9r interleukin 9 receptor [ Rattus norvegicus ]|
|Official Symbol :||IL9R|
|Synonyms :||IL9R; interleukin 9 receptor; interleukin-9 receptor;|
|Gene ID :||24500|
|mRNA Refseq :||NM_017021|
|Protein Refseq :||NP_058717|
|UniProt ID :|
|Pathway :||Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; IL-9 Signaling Path|
|Function :||interleukin-9 binding; interleukin-9 receptor activity;|
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Q&As (6)Ask a question
In pre-clinical trials, the IL9R significantly increased natural killer and CD4 + T cell levels in patients.
IL9R may play an important role in the treatment of central nervous system diseases and hematological diseases.
This needs to be further confirmed by large-scale clinical trials.
This can be achieved through in vitro molecular cell techniques and carefully designed in vivo animal models.
There have been no large-scale clinical studies to prove which diseases the recombinant IL9R protein can treat.
Some studies have suggested that the expression of IL9R in tumor cells may be associated with patient prognosis.
Customer Reviews (3)Write a review
IL-9R belongs to the cell membrane receptor family, which includes multiple subunits. Different types of IL-9R may have different structures and involve different signal transduction mechanisms, and these structural properties need to be fully considered during the production process. -
Purification of IL-9R is relatively complex due to its transmembrane structure and complexity. Common purification methods include affinity chromatography, centrifugation, gel filtration and other technologies to obtain high purity IL-9R. -
The biological activity of IL-9R is verified by using methods such as cell culture, cell chemotactic assay, or enzym-linked immunosorbent assay, which can evaluate the binding capacity and signaling effect of IL-9R with its ligand, such as IL-9. -
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