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ACVR1B

  • Official Full Name

    activin A receptor, type 1B

  • Overview

    This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a hete
  • Synonyms

    ACVR1B; activin A receptor, type 1B; activin receptor type-1B; ALK-4; activin receptor type IB; activin receptor-like kinase 4; serine/threonine-protein kinase receptor R2; Alk4; SKR2; ActRIB; ActR-IB; Acvrlk4; 6820432J04;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus
  • Rhesus Macaque
  • BTI-Tn-5B1-4 Cell
  • E.coli
  • E.coli expression system
  • HEK293
  • Human Cell
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Sf9 Insect Cell
  • Wheat Germ
  • C
  • Fc
  • His
  • Fc Chimera
  • Fc|His
  • GST
  • GST|His
  • hFc
  • His (Fc)
  • Avi
  • human|IgG1|Fc
  • N/A
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ACVR1B-529H Active Recombinant Human ACVR1B protein, hFc-tagged HEK293 hFc Met1-Glu126
Human ACVR1B-1916H Active Recombinant Human Activin A Receptor, Type IB HEK293 N/A
Human ACVR1B-249H Active Recombinant Human ACVR1B Protein, GST-tagged Insect Cell GST
Human ACVR1B-189H Active Recombinant Human ACVR1B, Fc Chimera Mammalian cells Fc Chimera
Human ACVR1B-528H Active Recombinant Human ACVR1B, Fc-tagged, Biotinylated Human Cell Fc
Human ACVR1B-645H Active Recombinant Human ACVR1B protein, His-tagged HEK293 His Ser 24 - Glu 126
Human ACVR1B-250H Recombinant Human ACVR1B Protein, GST-tagged Wheat Germ GST
Human ACVR1B-2596H Recombinant Human Activin A Receptor, Type IB BTI-Tn-5B1-4 Cell N/A
Human ACVR1B-5295H Recombinant Human Activin A Receptor, Type IB, GST-tagged Insect Cell GST
Human ACVR1B-231H Recombinant Human ACVR1B protein, GST/His-tagged E.coli GST/His
Human ACVR1B-240H Recombinant Human Activin A Receptor, Type IB, GST-tagged, Active Sf9 Insect Cell GST
Human ACVR1B-1584H Recombinant Human Activin A Receptor, Type IB Mammalian cells N/A
Human ACVR1B-560H Recombinant Human ACVR1B, Fc-His tagged Human Cell Fc/His
Human ACVR1B-2130HCL Recombinant Human ACVR1B cell lysate Human Cell N/A
Human ACVR1B-287H Recombinant Human ACVR1B Protein, His-tagged E.coli His Ser24~Glu126
Human ACVR1B-332H Recombinant Human Activin ACVR1B protein, Fc-tagged HEK293 human/IgG1/Fc 103
Human ACVR1B-082H Recombinant Human ACVR1B Protein, Fc-tagged HEK293 Fc 505
Human ACVR1B-865HF Recombinant Full Length Human ACVR1B Protein, GST-tagged In Vitro Cell Free System GST 505 amino acids
Human ACVR1B-165H Recombinant Human ACVR1B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human ACVR1B-1288H Recombinant Human ACVR1B Protein (N150-I505), Tag Free Insect Cell No tag N150-I505
Human ACVR1B-2614H Active Recombinant Human ACVR1B protein, hFc&His-tagged HEK293 hFc&His Met 1-Glu 126
Human ACVR1B-169H Recombinant Human ACVR1B Protein, His-tagged Human Cell His Ser24-Glu126
Human ACVR1B-0224H Recombinant Human ACVR1B Protein (Ser24-Glu126), C-His-tagged Mammalian cells C-His Ser24-Glu126
Human ACVR1B-1289H Recombinant Human ACVR1B Protein (N150-I505), His tagged Insect Cell His N150-I505
Human ACVR1B-0223H Recombinant Human ACVR1B Protein (Ser24-Glu126), His-tagged E.coli His Ser24-Glu126
Human ACVR1B-165H-B Recombinant Human ACVR1B Protein Pre-coupled Magnetic Beads HEK293
Human ACVR1B-2861H Recombinant Human ACVR1B protein, His-tagged HEK293 His Ser 19-Thr 137
Mouse Acvr1b-586M Active Recombinant Mouse Acvr1b Protein, Fc Chimera Mammalian cells Fc
Mouse Acvr1b-975M Active Recombinant Mouse Acvr1b Protein, Fc-tagged HEK293 Fc
Mouse Acvr1b-1M-B Recombinant Mouse Acvr1b Protein Pre-coupled Magnetic Beads HEK293
Mouse Acvr1b-5598M Recombinant Mouse Acvr1b Protein (Leu32-Glu126), C-Fc tagged Mammalian cells C-Fc Leu32-Glu126
Mouse Acvr1b-1M Recombinant Mouse Acvr1b Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Acvr1b-288M Recombinant Mouse Acvr1b Protein, His-tagged E.coli His Ile207~Val385
Rat ACVR1B-492R Recombinant Rat ACVR1B Protein Mammalian Cell His
Rat Acvr1b-8721R Recombinant Rat Acvr1b, Fc tagged Human Cell N/A
Rat ACVR1B-1206RCL Recombinant Rat ACVR1B cell lysate Human Cell N/A
Rat ACVR1B-148R-B Recombinant Rat ACVR1B Protein Pre-coupled Magnetic Beads HEK293
Rat ACVR1B-148R Recombinant Rat ACVR1B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ACVR1B-2179R Active Recombinant Rat ACVR1B protein, hFc-tagged HEK293 hFc Met1-Glu126
Cynomolgus Monkey ACVR1B-8815C Recombinant Cynomolgus ACVR1B, Fc tagged Human Cell Fc
Cynomolgus Monkey ACVR1B-1356CCL Recombinant Cynomolgus ACVR1B cell lysate Human Cell N/A
Homo sapiens (Human) RFL-820HF Recombinant Full Length Human Activin Receptor Type-1B(Acvr1B) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (24-505)
Rattus norvegicus (Rat) RFL-26303RF Recombinant Full Length Rat Activin Receptor Type-1B(Acvr1B) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (24-505)
Rhesus ACVR1B-93R Recombinant Rhesus ACVR1B protein, hFc-tagged HEK293 hFc Met1-Glu126
Rhesus Macaque ACVR1B-231R Recombinant Rhesus monkey ACVR1B Protein, His-tagged Mammalian Cell His
Rhesus Macaque ACVR1B-59R-B Recombinant Rhesus Macaque ACVR1B Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque ACVR1B-59R Recombinant Rhesus Macaque ACVR1B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ACVR1B Related Research Area

ACVR1B involved in several pathways and played different roles in them. We selected most pathways ACVR1B participated on our site, such as Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with ACVR1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cytokine-cytokine receptor interactionIL2RA;KITLGB;CCR6;IFNW1;IL11RA2;CXCL3;VEGFA;CRFB16;IL9
TGF-beta signaling pathwayPITX2;LFT2;RPS6KB2;LEFTY2;ACVR1;TFDP1;TGIF2;SMURF2;RBX1
Signaling pathways regulating pluripotency of stem cellsZIC3;DLX5;SETDB1;FZD1;PIK3CG;PCGF2;ACVR1C;AKT2;AKT1

ACVR1B has several biochemical functions, for example, ATP binding, SMAD binding, contributes_to activin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ACVR1B itself. We selected most functions ACVR1B had, and list some proteins which have the same functions with ACVR1B. You can find most of the proteins on our site.

Function Related Protein
ATP bindingAKT2;DNAJA2L;RTCB;KCNJ10;KIF23;PTK7A;MYH13;FUK;DDX43
SMAD bindingCOL1A2;SKOR2;BMP2;SKIA;COL5A2;SKOR1;FKBP1A;PML;SKIB
contributes_to activin bindingACVR1B;ACVR2A
activin receptor activity, type IACVRL1;ACVR1B;ACVR1C
contributes_to activin-activated receptor activityACVR1B;ACVR2A
contributes_to growth factor bindingTGFBR1;ERBB2;IL6ST;ACVR1B
inhibin bindingINHBA;INHA;ACVR2A;IGSF1;ACVR1B
metal ion bindingSMYD1A;SPON2;TRIM35-27;SOBPA;JADE3;NRP2B;PFKL;DMRT1;NINL
protein bindingKIAA1524;DCLRE1B;C9orf9;PURA;HEXIM1;DYRK1A;MMP9;CST5;TOR1B
protein serine/threonine kinase activityNUAK2;BMPR1AB;RAF1;PHKG1B;CASK;MAPK11;Aatk;STK3;WNK2
receptor signaling protein serine/threonine kinase activityACVR2AA;BMPR2A;ALPK2;SBK3;BMPR1A;ACVR1BA;STK25A;PANK1A;STK26
transmembrane receptor protein serine/threonine kinase activityACVR1;BMPR1BA;ACVR1BA;ACVR1B;ACVR2A;BMPR1BB;BMPR1AB;BMPR1B;TGFBR2
ubiquitin protein ligase bindingARRB1;TRAF3;OTUB1;PRKAR1A;UBE2V2;RRAGA;PRKACA;MAGEC2;NLK

ACVR1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ACVR1B here. Most of them are supplied by our site. Hope this information will be useful for your research of ACVR1B.

SMAD7; HSP90AB1; FKBP1A; XIAP; RXRA; PRKACB; BAG6; OS9; bosutinib

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