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Recombinant Human ACVR1B Protein, GST-tagged

Cat.No. : ACVR1B-250H
Product Overview : Human ACVR1B full-length ORF ( AAH00254.1, 1 a.a. - 505 a.a.) recombinant protein with GST-tag at N-terminal.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Jun 2010]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 81.29 kDa
AA Sequence : MAESAGASSFFPLVVLLLAGSGGSG PRGVQALLCACTSCLQANYTCETDG ACMVSIFNLDGMEHHVRTCIPKVEL VPAGKPFYCLSSEDLRNTHCCYTDY CNRIDLRVPSGHLKEPEHPSMWGPV ELVGIIAGPVFLLFLIIIIVFLVIN YHQRVYHNRQRLDMEDPSCEMCLSK DKTLQDLVYDLSTSGSGSGLPLFVQ RTVARTIVLQEIIGKGRFGEVWRGR WRGGDVAVKIFSSREERSWFREAEI YQTVMLRHENILGFIAADNKDNGTW TQLWLVSDYHEHGSLFDYLNRYTVT IEGMIKLALSAASGLAHLHMEIVGT QGKPGIAHRDLKSKNILVKKNGMCA IADLGLAVRHDAVTDTIDIAPNQRV GTKRYMAPEVLDETINMKHFDSFKC ADIYALGLVYWEIARRCNSGGVHEE YQLPYYDLVPSDPSIEEMRKVVCDQ KLRPNIPNWWQSYEALRVMGKMMRE CWYANGAARLTALRIKKTLSQLSVQ EDVKI
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Gene Name : ACVR1B activin A receptor, type IB [ Homo sapiens ]
Official Symbol : ACVR1B
Synonyms : ACVR1B; activin A receptor, type IB; ACVRLK4; activin receptor type-1B; ActRIB; ALK4; SKR2; activin receptor-like kinase 4; activin A receptor, type II-like kinase 4; serine/threonine-protein kinase receptor R2; ACTRIB;
Gene ID : 91
mRNA Refseq : NM_004302
Protein Refseq : NP_004293
MIM : 601300
UniProt ID : P36896

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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