Active Recombinant Rat ACVR1B protein, hFc-tagged

• Cat.No.: ACVR1B-2179R
• Product Overview: Recombinant Rat ACVR1B protein(NP_954700.1)(Met1-Glu126), fused with hFc tag, was expressed in HEK293.

Specification

• Source: HEK293
• Species: Rat
• Tag: hFc
• Form: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
• Bio-activity: Measured by its ability to bind with rat TDGF1-His in a functional ELISA.
• Molecular Mass: The recombinant rat ACVR1B/Fc is a disulfide-linked homodimer. The reduced monomer comprises 344 amino acids and has a predicted molecular mass of 38.4 kDa. The apparent molecular mass of the protein is approximately 42 and 34 kDa in SDS-PAGE under reducing conditions.
• Protein Length: Met1-Glu126
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: > 95 % as determined by SDS-PAGE
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
  Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: Acvr1b activin A receptor, type IB [ Rattus norvegicus ]
• Official Symbol: ACVR1B
• Synonyms: ACVR1B; activin A receptor, type IB; activin receptor type-1B; ALK-4; ACTR-IB; activin receptor type IB; activin A receptor, type 1B; activin receptor-like kinase 4; Serine/threonine-protein kinase receptor R2; Skr2
• Gene ID: 29381
• mRNA Refseq: NM_199230
• Protein Refseq: NP_954700