ANGPTL3

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ANGPTL3

Official Full Name angiopoietin-like 3
Background This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metablism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2. [provided by RefSeq, Feb 2013]
Synonyms ANGPTL3; angiopoietin-like 3; ANL3; ANG-5; FHBL2; ANGPT5; angiopoietin-related protein 3; angiopoietin 5;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • CHO
    • E.coli
    • Hamster
    • HEK293
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • FLAG
    • GST
    • His
    • T7
    • His-Avi
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ANGPTL3-117H Recombinant Human ANGPTL3 Protein, His-tagged E.coli His
    Mouse ANGPTL3-394M Recombinant Mouse ANGPTL3 Protein, His-tagged Insect Cell His
    Human ANGPTL3-399H Recombinant Human ANGPTL3 Protein, FLAG-tagged HEK293 FLAG
    Mouse Angptl3-1626M Recombinant Mouse Angptl3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human ANGPTL3-432H Recombinant Human ANGPTL3 Protein (Met1-Glu460), His-tagged Insect Cell His
    Mouse ANGPTL3-783M Recombinant Mouse ANGPTL3 Protein (Met1-Thr455), His-tagged Insect Cell His
    Human ANGPTL3-842H Recombinant Human ANGPTL3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human ANGPTL3-951H Recombinant Human ANGPTL3 protein, His-Avi-tagged HEK293 His-Avi
    Human ANGPTL3-951HB Recombinant Human ANGPTL3 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi
    Human ANGPTL3-101H Recombinant Human ANGPTL3, His-tagged E.coli His
    Human ANGPTL3-176H Recombinant Human ANGPTL3 protein, His-tagged HEK293 His
    Human ANGPTL3-26574TH Recombinant Human ANGPTL3, FLAG-tagged HEK293 FLAG
    Human ANGPTL3-27353TH Recombinant Human ANGPTL3, FLAG-tagged HEK293 FLAG
    Human ANGPTL3-32H Recombinant Human ANGPTL3 protein, His-tagged E.coli His
    Human ANGPTL3-397H Recombinant Human ANGPTL3, FLAG-tagged HEK293 Flag
    Human ANGPTL3-400H Recombinant Human Angiopoietin-like 3, FLAG-tagged HEK293 Flag
    Human ANGPTL3-487H Recombinant Human ANGPTL3 Protein, His-tagged CHO His
    Human ANGPTL3-555H Recombinant Human ANGPTL3 protein, His-tagged Hamster His
    Human ANGPTL3-556H Recombinant Human ANGPTL3 protein, GST-tagged Wheat Germ GST
    Human ANGPTL3-8862HCL Recombinant Human ANGPTL3 293 Cell Lysate HEK293 N/A
    Human ANGPTL3-9649H Recombinant Human ANGPTL3, GST-tagged E.coli GST
    Mouse Angptl3-173M Recombinant Mouse Angptl3 Protein, His-tagged, Biotinylated CHO His
    Mouse Angptl3-1819M Recombinant Mouse Angptl3 protein, His & GST-tagged E.coli His/GST
    Mouse Angptl3-1820M Recombinant Mouse Angptl3 protein, His & T7-tagged E.coli His/T7
    Mouse ANGPTL3-398M Recombinant Mouse ANGPTL3, Coiled-Coil Domain, His-tagged HEK293 His
    Mouse ANGPTL3-401M Recombinant Mouse Angiopoietin-like 3, FLAG-tagged HEK293 Flag
    Chicken ANGPTL3-3866C Recombinant Chicken ANGPTL3 Mammalian Cell His
    Zebrafish ANGPTL3-9329Z Recombinant Zebrafish ANGPTL3 Mammalian Cell His

    ANGPTL3 involved in several pathways and played different roles in them. We selected most pathways ANGPTL3 participated on our site, such as Integrins in angiogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with ANGPTL3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Integrins in angiogenesis EDIL3; MFGE8; CSF1R; CSF1; ANGPTL3

    ANGPTL3 has several biochemical functions, for example, enzyme inhibitor activity, growth factor activity, integrin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ANGPTL3 itself. We selected most functions ANGPTL3 had, and list some proteins which have the same functions with ANGPTL3. You can find most of the proteins on our site.

    Function Related Protein
    enzyme inhibitor activity CD46; PDE6H; CALU; NOTCH1; ATPIF1B; SLN; PPP1R12A; APBA3; UGT1A1; OAZ1A
    growth factor activity THBS4; IGF2; FGF6; CSF1B; CD320; REG1A; Pdgfa&Pdgfb; LEFTY1; GPI; FGF18A
    integrin binding L1CAM; CTGFA; S1PR3; VTN; COL3A1; NOV; TGFBI; PPAP2B; EGFL6; FN1
    phospholipase inhibitor activity ANXA2B; ANXA1C; ANXA3A; ANXA5; SNCB; APOC1; ANGPTL3; ANXA1B; ANXA1A; ANXA2A

    ANGPTL3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ANGPTL3 here. Most of them are supplied by our site. Hope this information will be useful for your research of ANGPTL3.

    ITGAV

    Nakajima, K; Kobayashi, J; et al. Antibodies to human angiopoietin-like protein 3: a patent evaluation of WO2012174178. EXPERT OPINION ON THERAPEUTIC PATENTS 24:113-119(2014).
    Chou, S; Lodish, HF; et al. Fetal liver hepatic progenitors are supportive stromal cells for hematopoietic stem cells. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 107:7799-7804(2010).

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