arf6
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  • Official Full Name
  • ADP-ribosylation factor 6
  • Background
  • ADP-ribosylation factor (Arf) proteins are low molecular weight GTP binding proteins that belong to the Ras GTPase superfamily. Arf proteins are grouped into three distinct classes based on amino acid sequence and structural similarity, with Arf6 as the s
  • Synonyms
  • ARF6; ADP-ribosylation factor 6; DKFZp564M0264
Cat.#:ARF6-26533THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ARF6 protein, His-tagged
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Cat.#:ARF6-749HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human ARF6 protein, GST-tagged
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Cat.#:ARF6-9803HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ARF, His-tagged
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Cat.#:ARF6-1842MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ARF6 Protein
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Cat.#:Arf6-3210MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse Arf6, His-tagged
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Cat.#:ARF6-752RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ARF6 Protein
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Cat.#:ARF6-380RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ARF6 Protein, His-tagged
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Cat.#:ARF6-3667CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ARF6
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Cat.#:ARF6-3369HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ADP-ribosylation Factor 6, His-tagged
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Cat.#:ARF6-8756HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ARF6 293 Cell Lysate
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Involved Pathway

ARF6 involved in several pathways and played different roles in them. We selected most pathways ARF6 participated on our site, such as Ras signaling pathway, Phospholipase D signaling pathway, Endocytosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with ARF6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ras signaling pathway
ABL2; GNB3; RELA; PRKCB; PTPN11; ELK1; RASGRP3; EFNA4; PDGFRB; RASAL1
Phospholipase D signaling pathway
TSC2; PIK3R2; PDGFD; CXCR1; PIK3R5; AKT2; RALB; AVPR2; GAB2; AGPAT5
Endocytosis
SH3GLB1; PIP5K1AB; ARF3; AP2M1A; RAB5AA; CLTCA; RHOAD; ARR3B; CHMP4C; CXCR4
Fc gamma R-mediated phagocytosis
GAB2; PLA2G4D; VAV3; MAPK1; DOCK2; RPS6KB1; PIK3R1; WASF2; MAPK3; PPAP2C

Protein Function

ARF6 has several biochemical functions, for example, GTP binding, GTPase activity, protein N-terminus binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ARF6 itself. We selected most functions ARF6 had, and list some proteins which have the same functions with ARF6. You can find most of the proteins on our site.
Function
Related Protein
Function GTP binding
Related Protein RAP1B; RHOF; RAB34A; REM2; AK3; RERGL; GNA11; GNA15.4; GBP6; GUCY2C
Function GTPase activity
Related Protein DNM2; MSTO1; RRAGD; RAB35; ATL2; RALAB; RALBA; GNAS; DIRAS1; ARF1
Function protein N-terminus binding
Related Protein RPA2; KCNQ2; KCNIP1; RND2; PEX14; MECP2; SCFD1; DCTN4; GTF2H2; CSNK2A1
Function protein binding
Related Protein C16orf59; ZNF16; APBA3; BLOC1S2; MIF4GD; DNAJC28; RPS6KA3; EDAR; GIT1; ROPN1L
Function thioesterase binding
Related Protein TRAF2; TRAF4; CALM3; RAC1; CDC42; ARF6; TRAF3; CALM; TRAF6; TRAF1

Interacting Protein

ARF6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ARF6 here. Most of them are supplied by our site. Hope this information will be useful for your research of ARF6.
KIF23

ARF6 Related Articles

van den Bosch, MTJ; Poole, AW; et al. Cytohesin-2 phosphorylation by protein kinase C relieves the constitutive suppression of platelet dense granule secretion by ADP-ribosylation factor 6. JOURNAL OF THROMBOSIS AND HAEMOSTASIS 12:726-735(2014).
Karnik, R; Ludlow, MJ; et al. Endocytosis of hERG Is Clathrin-Independent and Involves Arf6. PLOS ONE 8:-(2013).