bmi1
Share
  • Official Full Name
  • BMI1 polycomb ring finger oncogene
  • Background
  • BMI1 polycomb ring finger oncogene, also known as BMI1, is a protein which in humans is encoded by the BMI1 gene.
  • Synonyms
  • BMI1; BMI1 polycomb ring finger oncogene; PCGF4; RNF51; MGC12685; FLVI2/BMI1; B lymphoma Mo-MLV insertion region 1 homolog (mouse); polycomb group ring finger 4; Polycomb complex protein BMI-1; Polycomb group RING finger protein 4; RING finger protein 51; flvi-2/bmi-1; OTTHUMP00000019290; OTTHUMP00000019293; polycomb group protein Bmi1; B lymphoma Mo-MLV insertion region 1 homolog; murine leukemia viral (bmi-1) oncogene homolog
Cat.#:BMI1-27487HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BMI1, GST-tagged
+Inquiry
Cat.#:BMI1-316HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BMI1 Protein, His-tagged
+Inquiry
Cat.#:BMI1-10246HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BMI1, GST-tagged
+Inquiry
Cat.#:BMI1-135HTag:Arg
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BMI1 protein, Arginine-tagged
+Inquiry
Cat.#:BMI1-27486THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human BMI1
+Inquiry
Cat.#:BMI1-350HTag:His/MBP
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BMI1 protein, His/MBP-tagged
+Inquiry
Cat.#:BMI1-771HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human BMI1 Protein, His-tagged
+Inquiry
Cat.#:BMI1-2427MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse BMI1 Protein
+Inquiry
Cat.#:BMI1-1821CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken BMI1
+Inquiry
Cat.#:BMI1-8437HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human BMI1 293 Cell Lysate
+Inquiry

Involved Pathway

BMI1 involved in several pathways and played different roles in them. We selected most pathways BMI1 participated on our site, such as Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, MicroRNAs in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with BMI1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Signaling pathways regulating pluripotency of stem cells
PIK3R1; SKIL; SMAD4; MAPK12; AXIN2; KRAS; WNT8A; LHX5; MAP2K2; HESX1
Transcriptional misregulation in cancer
H3F3B; CD86; MPO; IL2RB; ZEB1; TLX1; KDM6A; BCL2L1; HIST1H3D; NR4A3
MicroRNAs in cancer
PTEN; IRS2; VIM; PRKCE; ABCB1A; PLCG1; CCNE2; MCL1; NOTCH4; BAK1

Protein Function

BMI1 has several biochemical functions, for example, RING-like zinc finger domain binding, protein binding, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by BMI1 itself. We selected most functions BMI1 had, and list some proteins which have the same functions with BMI1. You can find most of the proteins on our site.
Function
Related Protein
Function RING-like zinc finger domain binding
Related Protein RNF2; BMI1; UBE2I
Function protein binding
Related Protein TOMM22; NCOA1; SERBP1; CHMP1B; NOSTRIN; DTD2; SEC63; LSM2; DYNLT1; SUPV3L1
Function zinc ion binding
Related Protein Car4; PEX2; HDAC6; SLC25A46; LPP; USP3; RNF14; ADAM17; TRIM29; ZCCHC4

Interacting Protein

BMI1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with BMI1 here. Most of them are supplied by our site. Hope this information will be useful for your research of BMI1.
RNF2; RING1

BMI1 Related Articles

Sun, J; Wang, J; et al. Knockdown of Polycomb-Group RING Finger 6 Modulates Mouse Male Germ Cell Differentiation in Vitro. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY 35:339-352(2015).
Jagtap, JC; Dawood, P; et al. Expression and Regulation of Prostate Apoptosis Response-4 (Par-4) in Human Glioma Stem Cells in Drug-Induced Apoptosis. PLOS ONE 9:-(2014).