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CADM1

  • Official Full Name

    cell adhesion molecule 1

  • Overview

    Cell adhesion molecule 1 is a protein that, in humans, is encoded by the CADM1 gene.
  • Synonyms

    CADM1; cell adhesion molecule 1; IGSF4, immunoglobulin superfamily, member 4 , TSLC1, tumor suppressor in lung cancer 1; BL2; IGSF4A; Necl 2; NECL2; nectin like 2; RA175; ST17; SYNCAM; SYNCAM1; CADM1_HUMAN; DKFZp686F1789; IgSF4; Immunoglobulin superfamily member 4; MGC149785; MGC51880; NECL-2; Nectin-like protein 2; SgIGSF; Spermatogenic immunoglobulin superfamily; sTSLC 1; Synaptic cell adhesion molecule; TSLC-1; TSLC1; Tumor suppressor in lung cancer 1; nectin-like 2; TSLC1/Nectin-like 2/IGSF4; immunoglobulin superfamily, member 4; immunoglobulin superfamily, member 4D variant 2; sTSLC-1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • Fc
  • Myc
  • DDK
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CADM1-646H Active Recombinant Human CADM1, Fc-tagged, Biotinylated Human Cell Fc
Human CADM1-2183H Active Recombinant Human CADM1 protein, His-tagged HEK293 His Gln 45 - His 374
Human CADM1-647H Active Recombinant Human CADM1, Fc-tagged Human Cell Fc
Human CADM1-10650H Recombinant Human CADM1, His-tagged E.coli His 43-334a.a.
Human CADM1-0282H Recombinant Human CADM1 Protein, GST-Tagged Wheat Germ GST
Human CADM1-617H Recombinant Human cell adhesion molecule 1, His-tagged E.coli His
Human CADM1-1223H Recombinant Human CADM1 protein, His & GST-tagged E.coli His/GST Arg27~Val292 (Accession # Q9BY67)
Human CADM1-2527HCL Recombinant Human CADM1 cell lysate Human Cell N/A
Human CADM1-2260H Recombinant Human CADM1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human CADM1-428H Recombinant Human CADM1 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human CADM1-484H Recombinant Human CADM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human CADM1-35H Recombinant Human CADM1 protein, His-tagged E.coli His
Human CADM1-112H Recombinant Human CADM1 Protein, His-tagged HEK293 His 442
Human CADM1-1524HFL Recombinant Full Length Human CADM1 Protein, C-Flag-tagged Mammalian cells Flag
Human CADM1-484H-B Recombinant Human CADM1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Cadm1-5604M Active Recombinant Mouse Cell Adhesion Molecule 1, His-tagged Mammalian cells His
Mouse Cadm1-711M Active Recombinant Mouse Cadm1 Protein, His-tagged Mammalian cells His Ile42-Asp376
Mouse Cadm1-10651m Recombinant mouse Cadm1, GST-tagged E.coli GST 246-445a.a.
Mouse Cadm1-712M Recombinant Mouse Cadm1 protein, His-tagged HEK293 His Met1-His377
Mouse CADM1-2635M Recombinant Mouse CADM1 Protein Mammalian Cell His
Mouse Cadm1-1180M Recombinant Mouse Cadm1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Cadm1-1931M Recombinant Mouse Cadm1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse CADM1-1182M Recombinant Mouse CADM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Cadm1-5942M Recombinant Mouse Cadm1 Protein (Gln48-His388), C-Fc tagged Mammalian cells C-Fc Gln48-His388
Mouse Cadm1-1180M-B Recombinant Mouse Cadm1 Protein Pre-coupled Magnetic Beads HEK293
Mouse CADM1-1182M-B Recombinant Mouse CADM1 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CADM1 Related Articles
  • CADM1 Related Research Area

CADM1 involved in several pathways and played different roles in them. We selected most pathways CADM1 participated on our site, such as Cell adhesion molecules (CAMs), which may be useful for your reference. Also, other proteins which involved in the same pathway with CADM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell adhesion molecules (CAMs)CDH5;ITGA8;CLDN15LB;CD28;CD40;ITGB1B.2;CLDNJ;ITGB7;MHC2A

CADM1 has several biochemical functions, for example, PDZ domain binding, cell adhesion molecule binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CADM1 itself. We selected most functions CADM1 had, and list some proteins which have the same functions with CADM1. You can find most of the proteins on our site.

Function Related Protein
PDZ domain bindingF11R;PARK2;FZD7;ACOX1;GRIA1;FZD1;ERC1;ARHGEF16;GRM7
cell adhesion molecule bindingITGAL;PVRL1A;PTBP3;GLYCAM1;AMICA1;POSTN;CD1D;JUP;PVRL3B
protein bindingTTC8;CCND2;EZR;PRKX;PPP1R12C;IRAK1BP1;KNG1;Raet1a;CHAMP1
protein homodimerization activityCD226;LRP6;TYMS;XDH;CAMK2B;NKX2;NR6A1A;BCL2A1;PSMD7
receptor activityCD4;EIF2D;LILRB2;CD7;AMFR;ITGB3B;NOTCH4;ITGB1A;TLR4
receptor bindingHMGCL;PICK1;ADIPOQ;TMEM38A;PTK2;CLCF1;APLN;ICAM3;CSNK2B

CADM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CADM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CADM1.

PSMA6; ATF7IP; LIN7A; EPB41L3; ITGB4

Fossum, E; Grodeland, G; et al. Vaccine molecules targeting Xcr1 on cross-presenting DCs induce protective CD8(+) T-cell responses against influenza virus. EUROPEAN JOURNAL OF IMMUNOLOGY 45:624-635(2015).
Moiseeva, EP; Straatman, KR; et al. CADM1 Controls Actin Cytoskeleton Assembly and Regulates Extracellular Matrix Adhesion in Human Mast Cells. PLOS ONE 9:-(2014).
  • Q&As
  • Reviews

Q&As (5)

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How do genetic variations or mutations in the CADM1 gene affect its function, and what are the medical implications of these variations in diseases such as autism spectrum disorders and cancer? 01/31/2022

Mutations or genetic variations in CADM1 can lead to altered protein function, potentially contributing to the development of diseases like autism spectrum disorders and various cancers. Studying these variations helps uncover their specific roles in disease progression.

What is the role of CADM1 in cell adhesion, and how does it contribute to cellular processes in various tissues? 10/01/2021

CADM1 is a cell adhesion molecule that plays a crucial role in maintaining tissue integrity and mediating cell-cell adhesion. It is involved in various cellular processes, including tissue development, immune response, and neural cell connectivity.

Can you discuss the post-translational modifications of CADM1 and their relevance in cell signaling pathways and disease contexts? 05/08/2021

Post-translational modifications of CADM1, such as phosphorylation and glycosylation, play critical roles in modulating its interactions and functions. Understanding these modifications is important for unraveling disease mechanisms and potential therapeutic targets.

How does CADM1 contribute to the regulation of immune responses, particularly in the context of autoimmune diseases and immune cell interactions? 10/10/2019

CADM1 mediates immune cell interactions and regulates immune responses. Dysregulation of CADM1 has been implicated in autoimmune diseases like multiple sclerosis, where it affects immune cell adhesion and migration.

What are the current therapeutic approaches targeting CADM1 in cancer treatment, and what challenges exist in developing CADM1-specific therapies for clinical use? 02/14/2018

Therapeutic strategies targeting CADM1 in cancer treatment include antibody-based therapies and small molecule inhibitors. Challenges include ensuring specificity and minimizing potential side effects, given the diverse roles of CADM1 in different tissues.

Customer Reviews (3)

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Reviews
06/09/2021

    Good quality - it's an essential part of our research.

    05/17/2019

      I highly recommend this product!

      06/09/2018

        Friendly services!

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