Recombinant Full Length Human CADM1 Protein, C-Flag-tagged

• Cat.No.: CADM1-1524HFL
• Product Overview: Recombinant Full Length Human CADM1 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells.

Specification

• Description: Enables signaling receptor binding activity. Involved in several processes, including cell recognition; positive regulation of cytokine production; and susceptibility to natural killer cell mediated cytotoxicity. Located in plasma membrane. Implicated in breast carcinoma and prostate cancer. Biomarker of cervix uteri carcinoma in situ.
• Source: Mammalian cells
• Species: Human
• Tag: Flag
• Form: 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 48.3 kDa
• AA Sequence: MASVVLPSGSQCAAAAAAAAPPGLR LRLLLLLFSAAALIPTGDGQNLFTK DVTVIEGEVATISCQVNKSD DSVIQLLNPNRQTIYFRDFRPLKDS RFQLLNFSSSELKVSLTNVSISDEG RYFCQLYTDPPQESYTTITV LVPPRNLMIDIQKDTAVEGEEIEVN CTAMASKPATTIRWFKGNTELKGKS EVEEWSDMYTVTSQLMLKVH KEDDGVPVICQVEHPAVTGNLQTQR YLEVQYKPQVHIQMTYPLQGLTREG DALELTCEAIGKPQPVMVTW VRVDDEMPQHAVLSGPNLFINNLNK TDNGTYRCEASNIVGKAHSDYMLYV YDPPTTIPPPTTTTTTTTTT TTTILTIITDSRAGEEGSIRAVDHA VIGGVVAVVVFAMLCLLIILGRYFA RHKGTYFTHEAKGADDAADA
  DTAIINAEGGQNNSEEKKEYFITRT RPLEQKLISEEDLAANDILDYKDDD DKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining.
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 ug/mL as determined by microplate BCA method.
• Preparation: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Protein Families: Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)

Gene Information

• Gene Name: CADM1 cell adhesion molecule 1 [ Homo sapiens (human) ]
• Official Symbol: CADM1
• Synonyms: BL2; ST17; IGSF4; NECL2; RA175; TSLC1; IGSF4A; Necl-2; SYNCAM; sgIGSF; sTSLC-1; synCAM1
• Gene ID: 23705
• mRNA Refseq: NM_014333.4
• Protein Refseq: NP_055148.3
• MIM: 605686
• UniProt ID: Q9BY67