Recombinant Human CADM1 Protein, His-tagged

• Cat.No.: CADM1-112H
• Product Overview: Recombinant human CADM1 protein with His tag was expressed in HEK293.

Specification

• Description: Enables signaling receptor binding activity. Involved in several processes, including cell recognition; positive regulation of cytokine production; and susceptibility to natural killer cell mediated cytotoxicity. Located in plasma membrane. Implicated in breast carcinoma and prostate cancer. Biomarker of cervix uteri carcinoma in situ.
• Source: HEK293
• Species: Human
• Tag: His
• Form: Lyophilized
• Molecular Mass: 38.5 kDa
• Protein Length: 442
• AA Sequence: MASVVLPSGSQCAAAAAAAAPPGLR LRLLLLLFSAAALIPTGDGQNLFTK DVTVIEGEVATISCQVNKSDDSVIQ LLNPNRQTIYFRDFRPLKDSRFQLL NFSSSELKVSLTNVSISDEGRYFCQ LYTDPPQESYTTITVLVPPRNLMID IQKDTAVEGEEIEVNCTAMASKPAT TIRWFKGNTELKGKSEVEEWSDMYT VTSQLMLKVHKEDDGVPVICQVEHP AVTGNLQTQRYLEVQYKPQVHIQMT YPLQGLTREGDALELTCEAIGKPQP VMVTWVRVDDEMPQHAVLSGPNLFI NNLNKTDNGTYRCEASNIVGKAHSD YMLYVYDPPTTIPPPTTTTTTTTTT TTTILTIITDSRAGEEGSIRAVDHA VIGGVVAVVVFAMLCLLIILGRYFA RHKGTYFTHEAKGADDAADADTAII NAEGGQNNSEEKKEYFI
• Purity: > 98%
• Applications: WB; ELISA; FACS; FC
• Stability: This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
• Storage: At -20 centigrade.
• Concentration: 1 mg/mL
• Storage Buffer: PBS (pH 7.4-7.5). Sterile-filtered colorless solution.
• Reconstitution: Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.

Gene Information

• Gene Name: CADM1 cell adhesion molecule 1 [ Homo sapiens (human) ]
• Official Symbol: CADM1
• Synonyms: CADM1; cell adhesion molecule 1; IGSF4, immunoglobulin superfamily, member 4 , TSLC1, tumor suppressor in lung cancer 1; BL2; IGSF4A; Necl 2; NECL2; nectin like 2; RA175; ST17; SYNCAM; SYNCAM1; TSLC-1; nectin-like 2; nectin-like protein 2; truncated CADM1 protein; TSLC1/Nectin-like 2/IGSF4; synaptic cell adhesion molecule; tumor suppressor in lung cancer 1; immunoglobulin superfamily member 4; immunoglobulin superfamily, member 4; spermatogenic immunoglobulin superfamily; immunoglobulin superfamily, member 4D variant 2; IGSF4; TSLC1; Necl-2; sgIGSF; sTSLC-1; synCAM1; MGC51880; MGC149785; DKFZp686F1789
• Gene ID: 23705
• mRNA Refseq: NM_001098517
• Protein Refseq: NP_001091987
• MIM: 605686
• UniProt ID: Q9BY67