ccr9
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  • Official Full Name
  • Chemokine (C-C Motif) Receptor 9
  • Background
  • C-C chemokine receptor type 9, also called GPR-9-6 or CDw199, is a protein that in humans is encoded by the CCR9 gene. The protein encoded by this gene is a member of the beta chemoking receptor family. By radiation hybrid analysis and organization of BAC contigs by FISH on combed genomic DNA, the CCR9 gene within the CCR cluster was localized at 3p21.3. It is the receptor for chemokine SCYA25/TECK. This gene subsequently transduces a signal by increasing the intracellular calcium ions level. It is an alternative coreceptor with CD4 for HIV-1 infection. This gene may play a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract
  • Synonyms
  • C-C chemokine receptor type 9; GPR-9-6; CDw199; AI464239, CCR10, CCR9, Ccbp2, Cmkbr9, D6, CC-CKR-9, CDw199, GPR-9-6, GPR28, A130091K22Rik, Cmkbr10; Chemokine (C-C Motif) Receptor 9
Cat.#:CCR9-0699HTag:
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CCR9 Protein
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Cat.#:CCR9-716HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human CCR9
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Cat.#:CCR9-381CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus CCR9 Protein, His-tagged
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Cat.#:CCR9-3499CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CCR9
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Cat.#:CCR9-310HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CCR9 cell lysate
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Cat.#:Kit-1163Tag:
Source (Host):Species:
Product nameCCR9 CHO-K1 β-Arrestin GPCR Assay Kit
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Cat.#:Kit-0936Tag:
Source (Host):Species:
Product nameCYP2C9 Red Screening Kit
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Involved Pathway

CCR9 involved in several pathways and played different roles in them. We selected most pathways CCR9 participated on our site, such as Chemokine receptors bind chemokines, Chemokine signaling pathway, Class A/1 (Rhodopsin-like receptors), which may be useful for your reference. Also, other proteins which involved in the same pathway with CCR9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Chemokine receptors bind chemokines
CCL27; CCR1; CCL35.1; CCR7; CCL19A.2; CX3CR1; ACKR4; CXCR7B; AMCF-II; CCL35.2
Chemokine signaling pathway
PIK3CG; GNG13; CCL3; PXN; CCL21; PARD3; GNGT1; GRK4; CX3CR1; CXCL14
Class A/1 (Rhodopsin-like receptors)
RLN3; DRD3; CNR2; LPAR1; PENKB; EDN1; CCL35.1; GRP; NMB; CCL35.2
Cytokine-cytokine receptor interaction
IL6; GH2; MET; TNFRSF10C; IL7; TNFRSF10B; TNFSF15; CD70; BMPR2A; CXCL8B.3
G alpha (i) signalling events
CCR7; HEBP1; CXCR7B; CCR3; FPR-RS6; FPR-RS4; TAS2R3; RGS4; RGS11; AGT
GPCR downstream signaling
AKAP13; S1PR1; KALRN; PROK1; CXCL13; GPR55A; GPR65; TRPC3; PENKA; DGKB
GPCR ligand binding
OPN1SW; CNR1; TRH; LPAR2B; GNB5B; AMCF-II; PYYA; UTS2D; GPR55A; SSTR3
GPCRs, Class A Rhodopsin-like
LTB4R; ADORA3; GPR1; GPR12; CX3CR1; GPR31; GPR32; DRD4; GPR20; NPFFR2

Protein Function

CCR9 has several biochemical functions, for example, C-C chemokine receptor activity, chemokine receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CCR9 itself. We selected most functions CCR9 had, and list some proteins which have the same functions with CCR9. You can find most of the proteins on our site.
Function
Related Protein
Function C-C chemokine receptor activity
Related Protein CCR10; CCR1; CCR5; CCBP2; CCR8; CCR6A; CCR1L1; CCR3; GPR75; CCR7
Function chemokine receptor activity
Related Protein CCBP2; ACKR3B; RGRB; CCR8; GPR17; CMKLR1; CXCR3.1; CXCR3.2; CCR1L1; CXCR3

CCR9 Related Articles

Bakdash, G; Vogelpoel, LTC; et al. Retinoic acid primes human dendritic cells to induce gut-homing, IL-10-producing regulatory T cells. MUCOSAL IMMUNOLOGY 8:265-278(2015).
Danese, S; Panes, J; et al. Development of Drugs to Target Interactions Between Leukocytes and Endothelial Cells and Treatment Algorithms for Inflammatory Bowel Diseases. GASTROENTEROLOGY 147:981-989(2014).

CCR9 Related Gene Family

Chemokines Cytokines