| Description : |
The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to the chemokine receptor gene cluster region. Two alternatively spliced transcript variants have been described. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |
| Source : |
Wheat Germ |
| Species : |
Human |
| Form : |
Liquid |
| Molecular Mass : |
42 kDa |
| AA Sequence : |
MTPTDFTSPIPNMADDYGSESTSSM EDYVNFNFTDFYCEKNNVRQFASHF LPPLYWLVFIVGALGNSLVILVYWY CTRVKTMTDMFLLNLAIADLLFLVT LPFWAIAAADQWKFQTFMCKVVNSM YKMNFYSCVLLIMCISVDRYIAIAQ AMRAHTWREKRLLYSKMVCFTIWVL AAALCIPEILYSQIKEESGIAICTM VYPSDESTKLKSAVLTLKVILGFFL PFVVMACCYTIIIHTLIQAKKSSKH KALKVTITVLTVFVLSQFPYNCILL VQTIDAYAMFISNCAVSTNIDICFQ VTQTIAFFHSCLNPVLYVFVGERFR RDLVKTLKNLGCISQAQWVSFTRRE GSLKLSSMLLETTSGALSL |
| Applications : |
Antibody Production
Functional Study
Compound Screening |
| Usage : |
Heating may cause protein aggregation. Please do not heat this product before electrophoresis. |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : |
25 mM Tris-HCl of pH8.0 containing 2% glycerol. |
