|Official Full Name||CD82 molecule|
|Background||This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]|
|Synonyms||CD82; CD82 molecule; R2; 4F9; C33; IA4; ST6; GR15; KAI1; SAR2; TSPAN27; CD82 antigen; tspan-27; C33 antigen; tetraspanin-27; inducible membrane protein R2; metastasis suppressor Kangai-1; kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4));|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
CD82 involved in several pathways and played different roles in them. We selected most pathways CD82 participated on our site, such as Direct p53 effectors, Integrated Pancreatic Cancer Pathway, p53 signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CD82 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Direct p53 effectors||CEBPZ; DUSP1; EDN2; CSE1L; ARID3A; PCBP4; DDX5; RNF144B; PPM1J; FDXR|
|Integrated Pancreatic Cancer Pathway||RAPGEF3; BRF1; GPRC5A; PPP1R13L; MAPK4; RB1CC1; CASP12; AGA; CD82; JUND|
|p53 signaling pathway||GADD45G; SESN3; CD82|
CD82 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CD82 itself. We selected most functions CD82 had, and list some proteins which have the same functions with CD82. You can find most of the proteins on our site.
|protein binding||SDHA; CGGBP1; KRTAP3-3; TRIM27; VDAC1; TMEM123; SPRR2E; PLEKHM1; STK36; NDUFA9|
CD82 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CD82 here. Most of them are supplied by our site. Hope this information will be useful for your research of CD82.
VANGL1; CD19; NFKB1; NUP88; q9wmx2-pro_0000037550