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CTNNBIP1

  • Official Full Name

    catenin, beta interacting protein 1

  • Overview

    The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene.
  • Synonyms

    CTNNBIP1; catenin, beta interacting protein 1; beta-catenin-interacting protein 1; beta catenin interacting protein ICAT; ICAT; inhibitor of beta catenin and Tcf 4; MGC15093; inhibitor of beta-catenin and Tcf-4; beta-catenin-interacting protein ICAT;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • Myc|DDK
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human CTNNBIP1-11672H Recombinant Human CTNNBIP1, GST-tagged E.coli GST 1-81a.a.
Human CTNNBIP1-2585H Recombinant Human Catenin, Beta Interacting Protein 1, His-tagged E.coli His
Human CTNNBIP1-2084H Recombinant Human CTNNBIP1 Protein, GST-tagged Wheat Germ GST
Human CTNNBIP1-28030TH Recombinant Human CTNNBIP1, His-tagged E.coli His 81 amino acids
Human CTNNBIP1-3377H Recombinant Human CTNNBIP1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human CTNNBIP1-1844HFL Recombinant Full Length Human CTNNBIP1 Protein, C-Flag-tagged Mammalian cells Flag
Human CTNNBIP1-683H Recombinant Human CTNNBIP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human CTNNBIP1-5580H Recombinant Human CTNNBIP1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CTNNBIP1-2169H Recombinant Human CTNNBIP1 Protein (Met1-Gln81), N-His tagged E.coli N-His Met1-Gln81
Human CTNNBIP1-683H-B Recombinant Human CTNNBIP1 Protein Pre-coupled Magnetic Beads HEK293
Human CTNNBIP1-5814H Recombinant Human CTNNBIP1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CTNNBIP1-2318HF Recombinant Full Length Human CTNNBIP1 Protein, GST-tagged In Vitro Cell Free System GST 81 amino acids
Mouse Ctnnbip1-1368M Recombinant Mouse Ctnnbip1 protein, His & T7-tagged E.coli His/T7 Met1~Gln81 (Accession # Q9JJN6)
Mouse Ctnnbip1-2361M Recombinant Mouse Ctnnbip1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque CTNNBIP1-1081R Recombinant Rhesus monkey CTNNBIP1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque CTNNBIP1-906R-B Recombinant Rhesus Macaque CTNNBIP1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque CTNNBIP1-906R Recombinant Rhesus Macaque CTNNBIP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish CTNNBIP1-9135Z Recombinant Zebrafish CTNNBIP1 Mammalian Cell His
Chicken CTNNBIP1-5635C Recombinant Chicken CTNNBIP1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • CTNNBIP1 Related Articles

CTNNBIP1 involved in several pathways and played different roles in them. We selected most pathways CTNNBIP1 participated on our site, such as Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CTNNBIP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Wnt signaling pathwayCSNK1A1L;CUL1A;NFATC4;SKP1;PRKCB;PPARDB;MAPK8;NKD1;RUVBL1

CTNNBIP1 has several biochemical functions, for example, armadillo repeat domain binding, beta-catenin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CTNNBIP1 itself. We selected most functions CTNNBIP1 had, and list some proteins which have the same functions with CTNNBIP1. You can find most of the proteins on our site.

Function Related Protein
armadillo repeat domain bindingSTRN4;AXIN1;LEF1;CHD8;STRN;CTNNBIP1;TCF7L2;CNOT1;AXIN2
beta-catenin bindingCTNNA3;C;MED12L;CTNNA1;FAM123B;CD2AP;TCF7L1B;CHD8;CDH1
protein bindingC4BPB;USP20;CALM1;BAG5;SFRP5;PDLIM5;R3HDM2;MAP3K7IP3;PER2

CTNNBIP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CTNNBIP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CTNNBIP1.

CTNNB1; Ctnnb1; JUP

Canalis, E; et al. Wnt signalling in osteoporosis: mechanisms and novel therapeutic approaches. NATURE REVIEWS ENDOCRINOLOGY 9:575-583(2013).
Santiago-Gomez, A; Barrasa, JI; et al. 4F2hc-silencing impairs tumorigenicity of HeLa cells via modulation of galectin-3 and beta-catenin signaling, and MMP-2 expression. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1833:2045-2056(2013).
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