CTNNBIP1

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CTNNBIP1

Official Full Name catenin, beta interacting protein 1
Background The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene.
Synonyms CTNNBIP1; catenin, beta interacting protein 1; beta-catenin-interacting protein 1; beta catenin interacting protein ICAT; ICAT; inhibitor of beta catenin and Tcf 4; MGC15093; inhibitor of beta-catenin and Tcf-4; beta-catenin-interacting protein ICAT
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • T7
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human CTNNBIP1-11672H Recombinant Human CTNNBIP1, GST-tagged E.coli GST
    Human CTNNBIP1-2084H Recombinant Human CTNNBIP1 Protein, GST-tagged Wheat Germ GST
    Human CTNNBIP1-2585H Recombinant Human Catenin, Beta Interacting Protein 1, His-tagged E.coli His
    Human CTNNBIP1-28030TH Recombinant Human CTNNBIP1, His-tagged E.coli His
    Human CTNNBIP1-3377H Recombinant Human CTNNBIP1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Mouse Ctnnbip1-1368M Recombinant Mouse Ctnnbip1 protein, His & T7-tagged E.coli His/T7
    Rhesus Macaque CTNNBIP1-1081R Recombinant Rhesus monkey CTNNBIP1 Protein, His-tagged Mammalian Cell His
    Chicken CTNNBIP1-5635C Recombinant Chicken CTNNBIP1 Mammalian Cell His
    Zebrafish CTNNBIP1-9135Z Recombinant Zebrafish CTNNBIP1 Mammalian Cell His

    CTNNBIP1 involved in several pathways and played different roles in them. We selected most pathways CTNNBIP1 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with CTNNBIP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Wnt signaling pathway MAPK8; ROCK2A; TBL1X; FZD8A; FOSL1A; FZD1; RAC1; FZD5; FRAT2; FZD9B

    CTNNBIP1 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by CTNNBIP1 itself. We selected most functions CTNNBIP1 had, and list some proteins which have the same functions with CTNNBIP1. You can find most of the proteins on our site.

    Function Related Protein
    armadillo repeat domain binding STRN; CNOT1; LEF1; AXIN1; CHD8; CTNNBIP1; AXIN2; STRN4; CALCOCO1; TCF7L2
    beta-catenin binding SOX17; LZTS2A; PXN; GSK3B; PROP1; MED12L; TBL1X; TCF7L1B; PARK2; ASH2L
    protein binding REG3A; HELT; CDK4; PPARD; TMEM106C; TRIM21; PTPLAD1; SFTPD; PEX2; TEX13A

    CTNNBIP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CTNNBIP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of CTNNBIP1.

    CTNNB1; Ctnnb1; JUP

    Canalis, E; et al. Wnt signalling in osteoporosis: mechanisms and novel therapeutic approaches. NATURE REVIEWS ENDOCRINOLOGY 9:575-583(2013).
    Santiago-Gomez, A; Barrasa, JI; et al. 4F2hc-silencing impairs tumorigenicity of HeLa cells via modulation of galectin-3 and beta-catenin signaling, and MMP-2 expression. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH 1833:2045-2056(2013).

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