Recombinant Human CTNNBIP1, GST-tagged

• Cat.No.: CTNNBIP1-11672H
• Product Overview: Recombinant Human CTNNBIP1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-81a.a.
• Description: The protein encoded by this gene binds CTNNB1 and prevents interaction between CTNNB1 and TCF family members. The encoded protein is a negative regulator of the Wnt signaling pathway. Two transcript variants encoding the same protein have been found for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CTNNBIP1 catenin, beta interacting protein 1 [ Homo sapiens ]
• Official Symbol: CTNNBIP1
• Synonyms: CTNNBIP1; catenin, beta interacting protein 1; beta-catenin-interacting protein 1; beta catenin interacting protein ICAT; ICAT; inhibitor of beta catenin and Tcf 4; MGC15093; inhibitor of beta-catenin and Tcf-4; beta-catenin-interacting protein ICAT
• Gene ID: 56998
• mRNA Refseq: NM_001012329
• Protein Refseq: NP_001012329
• MIM: 607758
• UniProt ID: Q9NSA3
• Chromosome Location: 1pter-p36.31
• Pathway: Regulation of Wnt-mediated beta catenin signaling and target gene transcription, organism-specific biosystem; Wnt Signaling Pathway NetPath, organism-specific biosystem; Wnt signaling pathway, organism-specific biosystem; Wnt signaling pathway, conserved biosystem
• Function: armadillo repeat domain binding; beta-catenin binding; protein binding