cxcr6
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  • Official Full Name
  • Cxcr6 chemokine (C-X-C motif) receptor 6
  • Synonyms
  • CXCR6; chemokine (C-X-C motif) receptor 6; C-X-C chemokine receptor type 6; CXC-R6; CXCR-6; BONZO; STRL33; BB217514;
Cat.#:CXCR6-2183HTag:
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CXCR6 Protein
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Cat.#:CXCR6-2184HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CXCR6 Protein, GST-tagged
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Cat.#:CXCR6-4112MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse CXCR6 Protein
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Cat.#:CXCR6-1116RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CXCR6 Protein, His-tagged
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Cat.#:CXCR6-7160HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CXCR6 293 Cell Lysate
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Cat.#:Kit-0879Tag:
Source (Host):Species:
Product namedCK Screening Assay Kit
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Cat.#:Kit-0880Tag:
Source (Host):Species:
Product nameADK Assay Kit
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Cat.#:Kit-1203Tag:
Source (Host):Species:
Product nameCXCR6 Total GPCR Internalization Assay Kit
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Cat.#:Kit-1204Tag:
Source (Host):Species:
Product nameCXCR6 HEK 293 β-Arrestin GPCR Assay Kit
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Cat.#:Kit-1205Tag:
Source (Host):Species:
Product nameCXCR6 CHO-K1 β-Arrestin GPCR Assay Kit
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Involved Pathway

CXCR6 involved in several pathways and played different roles in them. We selected most pathways CXCR6 participated on our site, such as Chemokine receptors bind chemokines, Chemokine signaling pathway, Class A/1 (Rhodopsin-like receptors), which may be useful for your reference. Also, other proteins which involved in the same pathway with CXCR6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Chemokine receptors bind chemokines
CCBP2; CCL35.2; CCRL2; CXCL11.8; CXCL13; CCR7; AMCF-II; CCR6; CCR5; CX3CR1
Chemokine signaling pathway
CCL6; IL-8; CXCL3; CCL3L1; DOCK2; CCL5; GRB2; GNGT2; CCL17; VAV3
Class A/1 (Rhodopsin-like receptors)
GPR37L1; S1PR5B; ADRA2A; QRFPR; PENKA; FPR-RS6; ADRA2B; GPR68; CXCL13; LPAR2B
Cytokine-cytokine receptor interaction
TGFBR2; PDGFC; Il23a; TNFRSF10C; CXCL16; IFNA2; TP-1; LIF; TNFSF13; KITLG
G alpha (i) signalling events
LPAR2A; ANXA1A; HRH3; CCL27; RGS11; NMS; FPR-RS6; S1PR5B; AMCF-II; SOUL4
GPCR downstream signaling
SSTR5; OXER1; FPR-RS3; OPN4.1; APLNR; GPRC6A; CXCL11.8; PTGDR2; AGTR2; OXTRL
GPCR ligand binding
FFAR3; CHRM4; CHRM1; TAC3; NPS; OXGR1A.2; PRLH; PROKR2; GPR37B; GRP
Peptide GPCRs
SSTR5; SSTR4; TAC4; SSTR1; CXCR6; CX3CR1

Protein Function

CXCR6 has several biochemical functions, for example, C-X-C chemokine binding, C-X-C chemokine receptor activity, G-protein coupled receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CXCR6 itself. We selected most functions CXCR6 had, and list some proteins which have the same functions with CXCR6. You can find most of the proteins on our site.
Function
Related Protein
Function C-X-C chemokine binding
Related Protein CXCR3; HMGB1; CXCR6; CXCR7
Function C-X-C chemokine receptor activity
Related Protein CXCR2; CXCR6; CCBP2; CXCR3; CXCR4B; CCR9A; CXCR4A; CXCR4; CXCR7; CXCR5
Function G-protein coupled receptor activity
Related Protein GPR143; GPR152; OLFR13; RXFP3; OR5B2; TMTOPS2B; ADORA2AB; OLFCH1; GPR55; MC5RB
Function coreceptor activity
Related Protein CXCR4; ACKR3B; RAMP2; CD4; PVRL2; IGSF1; CCR5; CD28; ZP2; NRP1

CXCR6 Related Articles

Wehr, A; Baeck, C; et al. Pharmacological Inhibition of the Chemokine CXCL16 Diminishes Liver Macrophage Infiltration and Steatohepatitis in Chronic Hepatic Injury. PLOS ONE 9:-(2014).
Slauenwhite, D; Gebremeskel, S; et al. Regulation of Cytokine Polarization and T Cell Recruitment to Inflamed Paws in Mouse Collagen-Induced Arthritis by the Chemokine Receptor CXCR6. ARTHRITIS & RHEUMATOLOGY 66:3001-3012(2014).

CXCR6 Related Gene Family

Chemokines Cytokines