cyb5a
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  • Official Full Name
  • cytochrome b5 type A (microsomal)
  • Background
  • The protein encoded by this gene is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • CYB5A; cytochrome b5 type A (microsomal); CYB5, cytochrome b 5 , cytochrome b5 (microsomal); cytochrome b5; type 1 cyt-b5; CYB5; MCB5
Cat.#:CYB5A-001HTag:His
Source (Host):Insect cellSpecies:Human
Product nameRecombinant Human CYB5A Protein, His-tagged
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Cat.#:CYB5A-2208HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human CYB5A Protein, GST-tagged
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Cat.#:CYB5A-11744HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CYB5A, GST-tagged
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Cat.#:CYB5A-22HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CYB5A protein, His-tagged
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Cat.#:CYB5A-27555THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human CYB5A, His-tagged
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Cat.#:CYB5A-27557THTag:His
Source (Host):Species:Human
Product nameRecombinant Human CYB5A, His-tagged
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Cat.#:CYB5A-1700RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat CYB5A Protein
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Cat.#:CYB5A-1122RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey CYB5A Protein, His-tagged
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Cat.#:CYB5A-1144CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken CYB5A
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Cat.#:CYB5A-12352ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish CYB5A
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Cat.#:CYB5A-7146HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human CYB5A 293 Cell Lysate
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Involved Pathway

CYB5A involved in several pathways and played different roles in them. We selected most pathways CYB5A participated on our site, such as Metabolism, Metabolism of vitamins and cofactors, Metabolism of water-soluble vitamins and cofactors, which may be useful for your reference. Also, other proteins which involved in the same pathway with CYB5A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Metabolism
DAO; SLC16A1; SLC25A2; ALOX5B.2; ISCU; NUDT4A; HSD17B11; COX4I1; CPNE1; AGL
Metabolism of vitamins and cofactors
SLC46A1; CTRC; SLC25A32; SLC25A16; CYB5A; SLC2A3; SLC5A6B; KCNG4; MOCOS; NAMPT
Metabolism of water-soluble vitamins and cofactors
CYB5R3; ELA2; SLC25A32A; GSTO2; MOCOS; CYB5A; CTRB1; KCNG4; NAMPT; CBLC-1
Vitamin C (ascorbate) metabolism
CYB5A; CYB5R3; SLC23A2
cytochrome P450
CYP20A1; CYB5B; CYP4V2; CYB5A; CYB5R3; CYP4Z1; CYP4F12; CYP2W1; CYP2A7; POR

Protein Function

CYB5A has several biochemical functions, for example, aldo-keto reductase (NADP) activity, cytochrome-c oxidase activity, enzyme binding. Some of the functions are cooperated with other proteins, some of the functions could acted by CYB5A itself. We selected most functions CYB5A had, and list some proteins which have the same functions with CYB5A. You can find most of the proteins on our site.
Function
Related Protein
Function aldo-keto reductase (NADP) activity
Related Protein AKR1C4; HSD11B1LA; H2-KE6; MIOX; HSD3B6; AKR1C3; CYB5A; SDR16C6; AKR1C21; AKR1B1
Function cytochrome-c oxidase activity
Related Protein COX6C; COX7A2A; COA6; COX7A2L; COX5A; COX6A1; COX6B2; COX8A; COX5B; COX7C
Function enzyme binding
Related Protein WWOX; PEBP1; PRTN3; NOTCH1; EIF2AK3; UGT1A1; YWHAB; CASP2; HAND1; HOXA9
Function heme binding
Related Protein MB; TDO2; CYP1A2; CYBB; CYP2P7; CYP21A1; CYP2C55; CYP26B1; CYP2AA6; CYP2J5
Function metal ion binding
Related Protein Car9; ZFP367; TENC1; ACY1; ADAMTS16; ZNF285A; NRXN2A; HPDL; DGCR8; PLA2G3

Interacting Protein

CYB5A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CYB5A here. Most of them are supplied by our site. Hope this information will be useful for your research of CYB5A.
CYP3A5; TRAF6; UGT1A4; CYP2W1; q9wmx2-pro_0000037550