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Recombinant Human CYB5A Protein, His-tagged

Cat.No. : CYB5A-001H
Product Overview : Recombinant human CYB5A protein(1-108aa), fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
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Description : CYB5A, also known as cytochrome b5 isoform 1, is a member of membrane-bound cytochrome b5 family. It reduces ferric hemoglobin to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. This protein acts as an electron carrier for several membrane bound oxygenases.
Source : Insect cell
Species : Human
Tag : His
Form : Liquid
Molecular Mass : 13.3 kDa
AASequence : ADPMAEQSDEAVKYYTLEEIQKHNH SKSTWLILHHKVYDLTKFLEEHPGG EEVLREQAGGDATENFEDVGHSTDA REMSKTFIIGELHPDDRPKLNKPPE TLITTIDSSSSHHHHHH
N-terminal Sequence Analysis : Ala
Endotoxin : < 1.0 EU per 1 μg of protein (determined by LAL method)
Purity : > 90% by SDS - PAGE
Storage : Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 1.0 mg/mL (determined by Absorbance at 280nm)
Storage Buffer : In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.
Warning : For research use only. This product is not intended or approved for human, diagnostics or veterin
Gene Name : CYB5A cytochrome b5 type A [ Homo sapiens (human) ]
Official Symbol : CYB5A
Synonyms : CYB5A; cytochrome b5 type A; CYB5; MCB5; METAG; cytochrome b5; cytochrome b5 type A (microsomal); epididymis secretory sperm binding protein; type 1 cyt-b5
Gene ID : 1528
mRNA Refseq : NM_148923
Protein Refseq : NP_683725
MIM : 613218
UniProt ID : P00167

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can mutations in the CYB5A gene lead to clinical conditions? 05/05/2018

Yes, mutations in the CYB5A gene can lead to disorders such as methemoglobinemia, a condition characterized by the presence of elevated levels of methemoglobin in the blood.

What are the potential clinical implications of modulating CYB5A activity? 08/23/2017

Modulating CYB5A activity could have implications for drug efficacy, toxicity, and individualized drug dosing in clinical practice.

How does the expression of CYB5A vary in different populations? 07/10/2017

Studies have shown that the expression of CYB5A can vary among different populations, which could impact drug metabolism and response to medications.

Can CYB5A protein be a target for therapeutic interventions? 03/19/2017

Yes, given its importance in drug metabolism, the CYB5A protein could be a potential target for therapeutic interventions aimed at optimizing drug response and minimizing adverse effects.

Are there any drugs that specifically interact with CYB5A protein? 09/24/2016

Yes, certain drugs may interact with the CYB5A protein, affecting its activity and potentially leading to drug-drug interactions and altered metabolism.

Customer Reviews (3)

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09/04/2020

    Its high quality greatly enhances the reliability and reproducibility of experimental data.

    04/08/2020

      Whether I need expertise in experimental optimization or troubleshooting, I can rely on the manufacturer's support to promptly address any concerns or queries.

      09/25/2016

        CYB5A protein is known for its versatility and functionality, enabling researchers to explore various biological processes and molecular interactions.

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